Hungarian Wound Care Society

Assessing the Whole Patient Not Just "the Hole" Wound in the Patient: A Holistic Approach - Mdpi.com
Article by Sue V Abuleal (Victoria, Canada). This article explores how each of these elements influences the biological phases of wound healing emphasizing the importance of utilizing a holistic patient approach; thus, looking beyond the wound level to enhance healing, reduce complications, and improve patients' overall quality of life.

Effects of Traditional Chinese Medicine-Based Nursing Techniques on Postoperative Wound Pain in Patients Undergoing Open Thoracic Surgery - Scirp.org
Article by Yan Liu1orcid and Jingwen Zhang (Jingzhou, China - Journal of Biosciences and Medicines). TCM-based nursing techniques can effectively alleviate postoperative wound pain in patients undergoing open thoracic surgery, reduce the need for analgesic medication, and promote wound recovery.

Bacterial Cellulose Scaffolds for Advanced Wound Care: Immunomodulation, Mixed Biofilms, and Smart Regenerative Dressings - Mdpi.com
Article by Albert D. Luong, Moorthy Maruthapandi and John H. T. Luong (USA, Israel, Ireland - Macromol). This review reframes bacterial cellulose within the contemporary pathophysiology of chronic wounds, emphasizing its roles in immunomodulation, macrophage polarization, angiogenesis, mechanotransduction, and the disruption of mixed bacterial–fungal biofilms that characterize diabetic foot ulcers and other non-healing wounds.

Managing skin infections in burn patients: principles and pitfalls - Lww.com
Article by Giusy Tiseo, Sara Occhineri and Marco Falcone (Pisa, Italy - Current Opinion in Infectious Diseases). A structured, multidisciplinary team offers the most effective framework for improving outcomes in burn wound infections. Optimizing diagnostics, individualizing antimicrobial therapy, and aligning surgical timing with infection control measures are fundamental pillars. Future research should focus on prospective validation of integrated care pathways and on evaluating the real-world effectiveness of novel antimicrobial agents in burn-injured patients.

Regenerative Therapies for Cosmetic Dermatology for Patients with Diabetes Mellitus: Skin Aging, Aesthetic Concerns, and Evidence-Based Best Practices - Mdpi.com
Article by Tamara Tuma Odeh, Dillen A. Patel, Pradhyumna Mayur Pradeep, Jaiden A. Patel et al. (USA, Peru - IJMS). Clinical evidence specifically addressing aesthetic interventions in diabetic populations remains limited. A diabetes-informed approach to aesthetic dermatology that considers metabolic status, procedure selection, and post-procedural monitoring is therefore essential to optimize safety and therapeutic outcomes.

Formulation, Evaluation, and Antimicrobial Effect of Wound Healing Cream for Burns - Ijfmr.com
Article by Shani S, Thangavel M, Aiswarya R and Dinesh S (Coimbatore, India - IJFMR). The study highlights the potential of this animal-fat-enriched herbal formulation as a safe, natural, and effective burn wound-healing agent, providing scientific support for the traditional use of these medicinal plants in burn care management.

Using AI to Empower Self-Management in Diabetic Foot Ulcers: Practical Innovation at WoundCon Spring - Woundsource.com
Article by Mary Martin. Artificial intelligence is transforming healthcare—but how can it meaningfully support patients managing diabetic foot ulcers (DFUs) between visits? At WoundCon Spring, Mary Martin presents “Educating the Patient: Using AI to Empower Self-Management in DFUs,” a session in which she explores how technology can enhance—not replace—clinical judgment while improving long-term DFU outcomes. In this exclusive Q&A, she shares how AI can reduce cognitive overload, reinforce education, and strengthen patient participation in wound care.

Negative pressure wound therapy versus conventional debridement in subcutaneous abdominal wound healing in obese patients following obstetric/gynaecologic surgery - Nih.gov
Abstract by Ozan Karadeniz, Osman Murat Guler, Bugra Tunc and Mustafa Goksu (Istanbul, Turkey - J Wound Care).

Comparative Late Effects of Hemostatic Biomaterials on Wound Healing at 14 and 30 Days: An In Vivo Animal Study - Mdpi.com
Article by Polina Shabes, Julian-Dario Rembe, Arzu Mammadova, Katharina Henrika Beckamp et al. (Düsseldorf, Germany - JFB). The authors' findings suggest differential effects on cellular and molecular aspects of tissue remodeling; however, no conclusions can be drawn regarding overall healing quality or clinical safety, as no quantitative macroscopic or functional outcome measures were assessed.

Accelerating wound healing with mosaic partial reprogramming - Regmednet.com
It is well known that students who prepare in advance perform better on exams. Now, it appears that the skin can do the same. Rather than scrambling to repair itself only after injury occurs, a Korean research team has demonstrated that preconditioning a subset of skin cells into a “ready state” enables the tissue to initiate rapid and effective healing immediately upon injury.

Ultrasound-Assisted Wound Debridement for Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials - Mdpi.com
Article by Shasha Mei, Hua Chen and Jiezhi Dai (Shanghai, China - Biomedicines). Ultrasound-assisted wound debridement appears to be more effective than conventional debridement alone in improving healing rates and accelerating wound closure in diabetic foot ulcers. However, safety data were inadequately reported across most included studies, with adverse events poorly characterized.

Loneliness Slows Wound Healing by Triggering Persistent Inflammation, Study Finds - Sedaily.com
Article by Im Hye-Rin. Loneliness — often dismissed as a purely emotional condition — actually impairs the body's ability to heal physical wounds, according to new research. Researchers at the Medical University of South Carolina (MUSC) analyzed patients with chronic wounds and found that those who reported higher levels of loneliness showed markedly increased activity in inflammation-related genes. The study was published in the latest issue of the international journal "Advances in Skin & Wound Care".

Application of Honey Dressing in the Management of Postoperative Wounds, Ulcers, and Burns: A Systematic Review - Cureus.com
Article by Martin Schils, Clément Duveau, Grégory Van Doornick, Ibrahim Cherry et al. (Belgium). While the therapeutic benefits of honey have been acknowledged for centuries, contemporary studies consistently affirm its efficacy in the wound healing process, particularly when comparing honey-based dressings with conventional medical products currently in practice. Burns, emerge as the lesions where honey demonstrates its utmost effectiveness, likely related to a combination of antibacterial and healing-promoting properties. If confronted with escalating antibiotic resistance, the proactive utilization of honey to mitigate wound infections presents itself as a plausible and strategic option.

Scientists Create Healing Gel That Could Stop Chronic Wounds From Turning Deadly - Scitechdaily.com
Article by Jules Bernstein. The newly developed gel, tested in animal models, focuses on what is believed to be a central cause of chronic wounds: insufficient oxygen deep within damaged tissue. When oxygen levels are too low, wounds can remain stuck in an inflammatory state, creating an environment where bacteria thrive, and tissue breaks down instead of repairing itself.

Editorial: Skin Cancer and Wound Healing - Lww.com
Skin cancer is the most common cancer, with basal cell carcinomas being the most frequent type. These tumors often appear on sun-exposed skin as pearly-pink, translucent, fragile nodules, frequently accompanied by telangiectasias (thread-like surface blood vessels). They may develop surface erosions or ulcerations. Basal cell carcinomas are typically excised or curetted locally, with larger lesions or tumors, especially on the face, removed using Mohs microsurgery. This technique preserves surrounding skin through sequential removal and microscopic examination of tumor layers.

Nurses’ Knowledge and Practices Related to Wound and Peri-Wound Cleansing in Canada - Lww.com
Article by Kimberley LeBlanc, Samantha Wiesenfeld and Kevin Woo (Canada - Advances in Skin & Wound Care). The authors' findings underscore the need for enhanced education to bridge the gap between knowledge and practice. Aligning wound care practices with current evidence is essential to improving outcomes, preventing infection, and ensuring patient safety across Canadian health care settings.

A Call to Action: Enhancing Patient-Initiated Communication in Diabetic Below-Knee Amputation Cases for Improved Wound Center Outcomes - Lww.com
Abstract by Isabell Snee, Rachel Rohrich, Victoria H. Kim, Margaret E. Greer et al. (Washington, USA - Advances in Skin & Wound Care).

Dressing Decisions on the Go: Why Product Selection in Mobile Wound Care Directly Impacts Outcomes - Woundsource.com
Article by Jennifer J. Spector. The right dressing can change the trajectory of healing. See why product selection in mobile wound care plays a critical role in exudate control, infection prevention, operational efficiency, and patient outcomes across home-based settings.

From the Ground Up: The Impact of Comprehensive Diabetic Foot Assessment - Woundsource.com
Article by Jennifer J. Spector. Diabetes mellitus affects more than 37 million people in the United States, with an additional 96 million adults living with prediabetes. As prevalence increases, so too does the incidence of diabetes-related lower extremity complications.

When to Refer in Wound Care: Why Early Surgical and Vascular Consultation Saves Limbs and Lives - Woundsource.com
Article by Jennifer J. Spector. For clinicians early in their wound care careers, or even for more seasoned practitioners, one of the most challenging questions is not how to treat a wound—but when to refer it.

Self-regulating hydrogel for diabetic wound healing: From animal models to a pilot clinical study - Science.org
Article by Linlin Zhao, Shuwei Chen, Shuhan Chen, Yingxiao Sun et al. (Shanghai, China - ScienceAdvances). The authors' findings establish a self-pH–driven ion delivery strategy that targets both infection and tissue regeneration, offering a promising therapeutic platform for chronic diabetic wound care.

Effective Strategies for Managing Slough Wounds and Promoting Healing - Yourhealthmagazine.net
Understanding how to manage a slough wound is crucial for promoting optimal healing and preventing complications. Slough wounds feature a yellow or whitish tissue, which can be a barrier to healing if not treated properly. This article will provide insights into effective strategies for managing such wounds, emphasizing the importance of a comprehensive wound care plan and regular consultation with healthcare providers to ensure the best outcomes.

A case series: Application of 100% activated carbon cloth dressings in patients with chronic wounds with systemic comorbidities - Woundsinternational.com
Article by Nurul Hamizah Amran, Syafiqah Mohd Satali, Hamishatul Shamsiah Abdul Manaf, Norhasliza Zaina Abidin and Shukur Ahmad (Wounds). The use of activated carbon cloth (ACC) dressings was associated with substantial wound area reduction and preservation of periwound integrity in chronic wounds complicated by multiple comorbidities. These findings suggest that ACC dressings may represent a useful adjunctive approach for optimising the wound microenvironment in complex, hard-to-heal wounds. Nevertheless, larger prospective studies are required to confirm these findings and further establish their clinical effectiveness.

Europe faces a growing chronic wound crisis - time to act is now - Pa.media
Mölnlycke®, a global leader in MedTech, today welcomes the publication of Shaping the future of wound care in Europe, the first joint industry white paper from the MedTech Europe Wound Care Sector Working Group. The wound paper highlights the growing burden of chronic wounds and urges EU policymakers to elevate wound care as a strategic health priority across the EU.

Application of 3D-Bioprinting in Treatment of Chronic Wounds: A Review - Mdpi.com
Article by Miroslava Chortova, Elean Zanzov and Vanya Anastasova (Plovdiv, Bulgaria - Life). While significant technical challenges remain—including vascularization, scalability, and regulatory approval—the integration of advanced bioprinting techniques with regenerative medicine principles offers unprecedented opportunities for personalized chronic wound care and improved patient outcomes.

Overcoming resource and reimbursement barriers to best practice in the care of chronic wounds - Woundsinternational.com
Article by Sebastian Probst, Leanne Atkin, Joachim Dissemond, Domitilla Foghetti et al. (Wounds). This article presents three strategies (i.e. reframing cost perceptions, demonstrating economic value and addressing resource constraints) which together offer practical ways to overcome access barriers in the care of chronic wounds. However, success of strategies depends on the foundations laid throughout this series: the behavioural insights, knowledge frameworks and system-wide scalable improvements that create the conditions for effective access optimisation.

Offloading Explained: Why Reducing Pressure Is Critical for Wound Healing - Healogics.com
Offloading means reducing or removing pressure from an area of the body to help a wound heal or to prevent one from developing. If your provider recommends offloading, it means limiting weight-bearing or pressure on the affected area, most commonly the foot, ankle, leg, hips, or buttocks, depending on where the wound is located. For patients who are bed- or chair-bound, offloading may involve avoiding pressure on certain areas while sitting or lying down.

Reliability and Validation of Three Scoring Systems in the Assessment of Diabetic Foot Ulcers - Cureus.com
Article by Mruthunjaya S. Bevinamarad, Ramakanth Baloorkar, Shivanagouda S. Patil, Shailesh Kannur et al. (Vijayapura, India). Among the evaluated scoring systems, SINBAD showed superior predictive performance for adverse clinical outcomes and may serve as a practical tool for risk stratification in diabetic foot ulcer management.

The Healing Effect of Photobiomodulation on Venous Leg Ulcers: A Systematic Review and Meta‐Analysis - Nih.gov
Article by Aqella Rasul, Frederik Plum, Katrine Elisabeth Karmisholt and Klaus Kirketerp‐Møller (Copenhagen, Denmark - Wound Repair Regen.). This systematic review found no statistically significant improvement in venous leg ulcer healing with photobiomodulation compared with control treatment. Although photobiomodulation remains biologically plausible and appears safe at low fluences, current clinical evidence does not support its routine use as an adjuvant therapy for venous leg ulcers.

Advances in Nanotechnology-Assisted Delivery of TCM-Derived Bioactive Compounds for Wound Repair - Mdpi.com
Article by Lu Ren, Zefeng Zhao, Tianzihan Zhang, Meiting Kou et al. (Xianyang, China - Pharmaceutics). The authors suggest that nanodelivery approaches using TCM-derived compounds still need more careful study and steady improvement before they can be used more widely in wound care.

Effect of Statins on Wound Healing. A Systematic Review and Meta-Analysis of Preclinical Evidence - Wiley.com
Abstract by Ana M. Pachano-Bravo, Ovya Ganesan, Stephanie Mueller and Dennis P. Orgill (Boston, USA - Wound Rep and Regen).

Graphene Far-Infrared Therapy Enhances Diabetic Wound Healing Through Potential Mitigation of Oxidative Stress and Inflammation and Regulation of Chemokines and Macrophage Polarization - Mdpi.com
Article by Xinyu Jian, Xuanjun Wu, Xian Luo, Chengwei Cao et al. (Xiamen, China - IJMS). Chronic diabetic wound remain difficult to heal because persistent inflammation, oxidative stress, and impaired regeneration delay repair, while effective noninvasive options are limited. In this study, graphene-based far-infrared radiation therapy was evaluated in a streptozotocin-induced diabetic rat full-thickness wound model, and mechanisms were examined in vivo and in vitro.

Biocompatible Photocrosslinked Chitosan- and Gelatin-Based Hydrogels for Wound Healing Applications - Mdpi.com
Article by Isabella Nacu, Andreea Vasilache, Catalina Anisoara Peptu, Liliana Verestiuc and Andreea Luca (Iasi, Romania - Gels). All formulated hydrogels exhibit antioxidant capacity and protein stabilization properties, which are attributed to the presence of chitosan in their composition. The cytocompatibility, in vitro wound healing, and biological properties of the obtained hydrogels, as well as the drug release results, confirm their suitability in wound healing applications.

Reconstruction of Deep Partial-Thickness Burns With Ovine Forestomach Matrix: Results From a Prospective Observational Study - Cureus.com
Article by Patrick J. Kennedy, Michael Young, Kylie Wentworth, Nidhi Aravapalli et al. (USA). While ovine forestomach matrix’s (OFM) efficacy versus standard of care could not be established in the absence of a comparator group, this prospective observational study demonstrates the safety of OFM grafts when used in DPT burns, with healing in ~16 days, minimal pain, good cosmesis and patient satisfaction, and limited need for additional interventions.

Review on the impact of smoking on wound healing following facial procedures - Nih.gov
Article by Gunjan Chouksey, Amit Agrawal, Sudip Bhargava and Sunaina Tejpal Karna (Bhopal, India - Arch Craniofac Surg.). The authors' findings emphasize the importance of perioperative smoking cessation to improve healing and reduce preventable postoperative complications.

Hyperbaric Oxygen Therapy in Surgical Wound Healing and Tissue Salvage: A Structured Narrative Review - Cureus.com
Article by José Emiliano González Flores, Aarón Gonzalez Espinosa, Manuel Esaú Tamayo-Gómez, Stephanie Johanna Chon Pineda et al. (Mexico). HBOT represents a biologically active adjunct capable of enhancing surgical wound healing and tissue salvage through multifactorial regenerative mechanisms. As its applications continue to expand into reconstructive and aesthetic surgical domains, HBOT is positioned to play an increasingly integrative role within multidisciplinary perioperative care and complex wound management strategies.

Engineering the Healing Process: Advanced In Vitro Wound Models and Technologies - Mdpi.com
Article by Filippo Renò, Mario Migliario and Maurizio Sabbatini (Italy - Biomedicines). The authors conclude that the future of wound healing research depends on integrating vascular and immune components within these platforms to achieve truly human-relevant, personalized diagnostic and therapeutic tools.

Safety and Efficacy of Beraprost Sodium Combined with Negative Pressure Drip Irrigation in the Treatment of Diabetic Foot Ulcer: A Retrospective Cohort Study - PubMed
Abstract by Dian Zhou and Wen Wang (Wuxi, China - Int J Low Extrem Wounds).

Hyaluronic Acid-Based Gels and Biomaterial Systems for Oral Wound Healing: Design and Clinical Translation - Mdpi.com
Article by Vlad Constantin, Ionut Luchian, Dragos Ioan Virvescu, Mihaela Scurtu et al. (Iasi, Romania - Gels). Substantial heterogeneity exists regarding molecular weight, formulation, concentration, and application protocols, which limits direct comparison between studies and precludes definitive conclusions.

Doctoral thesis confirms algae have strong wound-healing, skin-protective, and immune-supporting properties - Tlu.ee
Chronic wounds affect approximately 2% of the population in developed countries. Existing treatments are expensive and may cause side effects. In his doctoral thesis, Amal D. Premarathna shows that a promising alternative to synthetic wound care treatments may come from nature—namely, algae. Some beneficial algae species are also found in Estonia.

Management of heel ulcers in diabetes - PubMed
Abstract by Anubhav Gupta and Subhash Rao Yadav Nagam (New Delhi, India - Indian J Thorac Cardiovasc Surg).

Peritoneal macrophages regulate distal wound healing via endocrine release of plasma fibronectin - Jci.org
Article by Lilian Salm, Simone N. Zwicky, Daniel Spari, Tural Yarahmadov et al. (Switzeland, Canada, Brazl - J Clin Invest). The authors' results suggest that peritoneal macrophages, strategically positioned in the peritoneal cavity, serve as a source of circulating fibronectin, promoting matrix formation and accelerating wound healing at distant sites.

Drug-releasing stitches aim to reduce inflammation and improve healing - News-medical.net
Deep cuts from accidents or surgeries require stitches, typically followed by oral anti-inflammatory medications like ibuprofen. While these medications help with pain, they don't act specifically on the wounds. Consequently, the site of the stitches can get inflamed, which could slow healing and lead to scarring. Now, researchers at Ouachita Baptist University are creating stitches loaded with anti-inflammatory drugs to deliver the medication directly to the injury.

Nutritional Needs for Wound Healing in Older Adults - Healogics.com
When you are healing from a wound, what you eat matters more than you might think. As you get older, your body’s nutritional needs change, and meeting those needs plays a critical role in how well and how quickly wounds heal. With the right approach to nutrition for older adults, you can actively support your recovery and overall wellness. This guide explains how nutrition affects wound healing in older adults and offers practical, realistic ways to nourish your body during recovery.

AI-driven OCT imaging system enables precise wound healing assessment - News-medical.net
No matter the size or severity, wounds on human skin are difficult to monitor while they heal. Biopsies disrupt the wound site and are too invasive for routine, repeated monitoring, and most medical imaging devices that could do the job are large, expensive and booked up with more pressing diagnostics. Clinicians typically resort to visual inspection or quick measurements of the wound's size over time. Based on research completed as part of a multi-year collaboration with Nokia Bell Labs, biomedical engineers at Duke University are developing a solution. Using a custom-built optical coherence tomography (OCT) imaging system together with artificial intelligence (AI) models grounded in a deep understanding of tissue regeneration, researchers have shown they can accurately and objectively measure the progress of wounds healing over time.

Study reveals new way to fully regenerate the scarred skin - News-medical.net
Could wounded skin someday regrow perfectly without scars? A new study by Harvard stem cell biologists published March 20 in Cell reveals a way to fully regenerate skin by unblocking an embryonic healing mechanism that shuts off after birth. Demonstrated on mice, the study suggests a potential means to develop similar therapies in human patients.

EPCR in Wound Healing: Mechanisms of Action and Therapeutic Potential - Mdpi.com
Article by Hui Wang, Lyn March, Christopher J. Jackson, Marita Cross and Meilang Xue (Sydney, Australia - Cells). While therapeutic potential has been shown in animal models, translating EPCR (endothelial protein C receptor) mediated therapies to clinical application faces many challenges, including wound heterogeneity, dosage control, targeted delivery, and potential bleeding risks.

Effectiveness of silver and iodine dressings on wound healing: a systematic review and meta-analysis - Bmjopen.bmj.com
Article by Yan Jiang, Qijian Zhang, Hongjuan Wang, Maritta Välimäki et al. (China - BMJ Open). Silver dressings, demonstrating a comparable healing rate to iodine dressings, significantly reduce healing time, suggesting their potential as a superior adjunct in wound care.

Osteopontin promotes lesion repair during Staphylococcus aureus skin infections - Biorxiv.org
Article by Emily E Neville, Mari L Shinohara, Jennifer Y Zhang, Abhay PS Rathore and Soman N Abraham (Singapore, USA). The authors' findings highlight the importance of specific neutrophil subtypes and osteopontin (OPN) signaling as critical mediators in infected tissue repair. Further our study suggests that modulating OPN may represent a promising therapeutic strategy to accelerate infected tissue repair.

Nurses’ Knowledge and Practices Related to Wound and Peri-Wound Cleansing in Canada - Lww.com
Article by Kimberly LeBlanc, Samantha Wiesenfeld and Kevin Woo (Canada, UK, Australia - Advances in Skin & Wound Care). The authors' The findings underscore the need for enhanced education to bridge the gap between knowledge and practice. Aligning wound care practices with current evidence is essential to improving outcomes, preventing infection, and ensuring patient safety across Canadian health care settings.

Wearable devices for detection and treatment of chronic wounds - Cell.com
Article by Pancheng Zhu, Zeyan Zhou, Jiaqi Ding, Zheng Dou et al. (Singapore, China - Cell Reports Physical Science). The authors highlight closed-loop device systems that combine sensing and therapy that enables automated, precise, and dynamic wound care. In addition, engineering challenges and future research directions are discussed to realize personalized and scalable solutions for chronic wounds. They expect this review to serve as a comprehensive reference for researchers, clinicians, and engineers pursuing next-generation wound-management technologies.

Green tea extracts clinical examination in humans’ wounds healing process: A case study - Wjarr.com
Article by Levan Gulua, Tamar Khutsidze and Tamar Turmanidze (Georgia - World Journal of Advanced Research and Reviews). Green tea extract was shown to be an effective remedy of various infectious, inflammatory, tropical and other after surgery complicated wounds in the process of recovery of injured tissues. Recovery processes were described in details including rate of regeneration process and symptomatic parameters.

Chronic Wound Healing: Research Advances from Pathological Mechanisms to Natural Herbal Active Ingredients and Material Delivery Systems - Mdpi.com
Article by Mengqing Yuan, Yufeng Liu, Xiaoyin Peng, Zhenjun Li and Mingsheng Lei (China - Molecules). Deepening our understanding of the biological mechanisms underlying chronic wounds, coupled with advanced biomaterial technologies, will propel clinical treatment toward more precise and efficient outcomes.

Electronic Skins for Advanced Wound Healing: Biomimetic Thermoregulation and Bioelectrically Active Systems - Nih.gov
Article by Nianhao Xue, Wenhao Guan, Tanghao Xia and Kexue Sun (Nanjing, China - Polymers (Basel)). In this article the structural innovations and design strategies for biomimetic thermotherapeutic electronic skins based on thermoelectric polymer composites and interactive temperature biomimetic regulation are summarized.

How to perform a simple wound assessment - Rcn.org.uk
Optimal assessment and timely, evidence-based treatments are not optional – they’re essential for improving outcomes, restoring dignity, and ensuring the best possible quality of life for your patients.

Healing Better at Home with Quality Wound Management and Nutrition - Asaging.org
Article by Natalie Kahle and Desiree Lacandola. As advanced practice providers working in mobile wound management, we have seen firsthand how bringing expert treatment directly to patients’ homes transforms lives—especially for older adults and those with limited mobility. Our goal is to meet patients where they are, delivering high-quality wound management that not only accelerates healing but also restores their personal sense of well-being. In this post we outline opportunities to improve wound healing outcomes through a mobile wound management model and its standardized protocols, including critical components like quality nutrition care.

Effect of Quercetin on Wound Healing and Tissue Adhesion - Intechopen.com
Article by Percin Karakol. This review synthesizes current knowledge on the molecular and biochemical mechanisms by which quercetin modulates wound healing, emphasizing its therapeutic potential. It further examines strategies to optimize dosing, including nanotechnological approaches that enable the transition from natural compounds to bioengineered therapeutic platforms.

New 3D-printed medicated patches show promise for chronic wound healing - News-medical.net
A team of University of Mississippi researchers is developing a way to use 3D printed medicated patches to help close persistent sores and ulcers. The researchers in the School of Pharmacy have created a customizable wound scaffold that delivers natural, biodegradable antibacterials over time to encourage healing. Researchers Michael Repka, distinguished professor of pharmaceutics and drug delivery; Sateesh Vemula, postdoctoral researcher; and doctoral candidate Nouf Alshammari published their results in the European Journal of Pharmaceutics and Biopharmaceutics.

Myrrh Oil-Based Nanoemulsion Loaded with Curcumin and Insulin: Development, Characterization, and Evaluation of Enhanced Antibacterial and Diabetic Wound-Healing Activity - Mdpi.com
Article by Ayman Salama, Mona Qushawy, Nehal Elsherbiny, Helal F. Hetta et al. (Saudi Arabia, Egypt - Pharmaceutics). The CUR-INS-NEG emerges as an effective system for diabetic wound management, delivering complementary anti-inflammatory, antioxidant, and tissue-regenerative effects of myrrh oil, curcumin, and insulin.

Cytoprotection as a Unifying Strategy for Hemorrhage and Thrombosis: The Role of BPC 157 and Related Therapeutics - Mdpi.com
Article by Predrag Sikiric, Ivan Barisic, Mario Udovicic, Martina Lovric Bencic et al. (Zagreb, Croatia - Pharmaceuticals). This review addresses the hemorrhage/thrombosis ideal agent problem from a cytoprotective perspective (decreased hemorrhage and thrombosis to preserve and reestablish homeostasis). It proposes the stable gastric pentadecapeptide BPC 157, which acts as a cytoprotective mediator. In rodents, BPC 157 can simultaneously counteract hemorrhage and thrombosis without directly affecting the coagulation cascade (aggregometry, thromboelastometry).

Negative pressure wound therapy use: recommendations from a South African panel of experts - PubMed
Abstract by Ethel Andrews, Fébé Bruwer, Jacques Goosen, Nick Kairinos et al. (South Africa - J Wound Care).

3D-Bioprinted Hydrogels Based on Calcium Alginate and Turmeric (Curcuma longa L.): Comprehensive Structural, Functional, and Biological Evaluation for Advanced Wound Healing Applications - Acs.org
Article by Rafaela Prediger dos Anjos, Paula de Abreu Fernandes, Hernane da Silva Barud, Marina de Lima Fontes et al. (São Paulo, Brazil - ACS Omega). The authors' findings highlight the versatility of CA/CR hydrogels, which combine swelling capacity, thermal stability, and controlled release of CR.

Toe and Flow – The Power of Collaboration in Limb Preservation - Woundsource.com
Edited by Jennifer J. Spector. Diabetes and peripheral artery disease contribute to a growing global epidemic of chronic wounds and limb loss. In the United States alone, non-traumatic lower extremity amputations exceed approximately 150,000 annually, with a disproportionate share linked to diabetes and CLTI.

Outcomes of Lower Extremity Nerve Decompression for Painful Diabetic Peripheral Neuropathy: A Retrospective Cohort Study - Springer.com
Article by Chenlong Liao, Shuo Li, Wenxiang Zhong, Yayuan Tian and Wenchuan Zhang (Shanghai, China - Neurol Ther.). Lower extremity nerve decompression (LEND) demonstrated long-term efficacy in alleviating pain and concurrently improving the pain-related interference and psychological status of patients with painful diabetic peripheral neuropathy. Younger age and lower latest BM were revealed to be independently associated with pain relief following LEND.

Wound Salvage After Total Ankle Replacement: Multidisciplinary Management of Postoperative Dehiscence - Hmpgloballearningnetwork.com
Edited by Jennifer J. Spector. Prompt surgical debridement, negative pressure wound therapy (NPWT), and infectious disease consultation can prevent progression to deep infection and prosthetic failure following Total Ankle Replacement. Collaboration between foot and ankle surgery, infectious disease, and plastic surgery enables structured escalation of care—particularly when soft tissue compromise threatens implant viability.

From Eradication to Holistic Regeneration: Pharmaceutics Strategies for Reshaping Gastric Homeostasis Against H. pylori Infection - Mdpi.com
Article by Qingsong Qu, Wanhong Zhu, Xingjian Song, Jingqi Zeng et al. (Beijing, China - Pharmaceutics). The review concludes with an analysis of postbiotics and the proposed holistic strategy, offering a promising therapeutic framework for mitigating the inflammation-to-cancer transition and promoting gastric health remodeling.

Mental Health in Wound Care: Why It Matters and What You Can Do - Wcei.net
Article by Aliza Inbari. Wound clinicians already do the hard technical work; adding systematic attention to mental health magnifies impact. Brief screening, empathetic communication, pain control, targeted referrals, and collaboration with mental-health and social resources are practical steps that improve both quality of life and, often, outcomes.

Natural Extracts in Skin Repair and Wound Healing: Phytochemical Mechanisms and Dermopharmaceutical Perspectives - Mdpi.com
Article by Niki Tertipi, Vasiliki Sofia, Eleni Sfyri, Eleni Andreou (Athens, Greece - Molecules). This review provides a mechanism-informed synthesis of current evidence, highlighting how phytochemical diversity, molecular signalling pathways, and dermopharmaceutical formulation strategies collectively shape the therapeutic potential of plant-derived extracts in cutaneous wound healing and may guide future mechanistic and translational research in phytochemical-based wound therapeutics.

Pilot Study: Soft-tissue Healing After Augmented Closure of Traumatic Injuries With Synthetic Electrospun Fiber Matrix - Lww.com
Article by Christopher Crosgrove (Memphis, USA - Plastic & Reconstructive Surgery-Global Open). Subdermal synthetic electrospun fiber matrix incorporation during primary closure resulted in complete soft tissue healing and low rates of major complications. This pilot study indicated that SEFM may be used to achieve primary closure and avoid advanced reconstructive procedures.

Probiotic and Postbiotic Delivery Systems for the Management of Chronic Wounds: A Review of Emerging Strategies - Cureus.com
Article by Maja Karmińska, Krystian Czernikiewicz, Wiktoria Głowacka-Kamińska, Natalia Skrzypska et al. (Poland). Current evidence suggests that probiotic-based dressings could serve as a promising adjunctive strategy in the management of chronic wounds; however, further well-designed clinical trials are necessary to validate efficacy, identify optimal strains and carriers, and assess long-term safety. While a large body of in vitro and animal model data exists, robust evidence from randomized controlled trials in humans remains scarce.

Pharmacological and Adjunctive Wound Healing Interventions in the Elderly: A Systematic Review and Meta-Analysis with Implications for Pharmacy Practice - Pharmacypractice.org
Article by Patsanan Kulla, Thanaporn Thakolpattanakul, Thanakrit Thakolpattanakul, Khemjira Pinyoying és Prayuth Poowaruttanawiwit (Thailand - Pharmacy Practice). Pharmacist-relevant interventions, particularly biological dressings and nutritional strategies, demonstrate clinically and economically meaningful benefits in elderly wound care. The authors' findings support the integration of pharmacists into geriatric wound management protocols and highlight the need for geriatric-specific, high-quality trials.

Educational Value and Reliability of Exosome Therapy Videos on YouTube: A Cross-Sectional Quality Assessment - Wiley.com
Article by Emrah Işıktekin and Salih Kılıç (Balikesir, Turkey - International Wound Journal). The discrepancy between the scientific advancements in the fields of regenerative medicine, dermatology and plastic surgery and the accessibility of online educational resources, highlights the necessity for professional health organisations to furnish accessible, evidence-based materials that accurately demonstrate the therapeutic potential of exosomes in wound healing.

Human Placental Mesenchymal Stem Cell-Derived Exosomes in Wound Healing and Scar Therapy: A Systematic Review and Meta-analysis - Academic.oup.com
Article by Greg Chernoff (Indianapolis, USA - Aesthetic Surgery Journal). hpMSC-derived exosomes demonstrate significant promise for wound healing optimization and scar therapy applications, supported by robust meta-analytic evidence from preclinical studies. The comprehensive safety profile across multiple administration routes and clinical indications, combined with strong preclinical efficacy data, supports continued investigation and development.

Innovative microneedle technology for diabetic wound healing - Eurekalert.org
Researchers from Nanjing Drum Tower Hospital, Southeast University, and Wenzhou Medical University have developed a novel microneedle patch that combines MXene hydrogel with nitric oxide (NO) and hypoxia-inducible factor-1α (HIF-1α) plasmid for enhanced diabetic wound treatment. This study, published in the journal Engineering, presents a promising approach to addressing the chronic and non-healing wounds often associated with diabetes.

Navigating the use of GenAI in wound care communication - Wouds-uk.com
Article by Samantha Holloway. The evidence discussed here suggests that AI tools have the potential to help address disparities in health literacy related to wound care. They may enhance patient education, support clearer communication, and provide accessible, personalised guidance that encourages engagement in wound management.

Electrospun nanofibers and electrical stimulation: a synergistic approach for chronic wound management - Rsc.org
Article by Jéssica Lopes, Maria Teresa Cruz, Fernando Ramos and Juliana R. Dias (Portugal - Journal of Materials Chemistry B). This review provides a concise summary of the skin structure, the wound healing process and the effects of electrical stimulation (ES) at various stages of healing. It also explores advanced electrospun-based wound dressings, focusing on the synergistic potential of combining ES with conductive electrospun dressings to optimize chronic wound healing outcomes.

Efficacy of Platelet-Rich Plasma and Polyvinyl Alcohol Wound Dressing in Open Wound Healing: First Results from an Experimental Rat Mode - Karger.com
Article by Umit Akin Dere; Fatma Altintas; Baris Albuz; Nazli Çil et al. (Turkey - Eur Surg Res). The relatively small sample size, absence of a PRP-only group, and short observation period limit the generalizability of these findings. Within these constraints, the results indicate a potential synergistic role of PRP and PVA scaffolds in promoting wound repair, supporting further studies with larger cohorts and standardized PRP preparation before clinical translation.

Incisional Hernia Development: Wound Healing Gone Wrong? - Nih.gov
Article by Asim A Abbas, Paul Gunning, Srinivas Chintapatla and Roland Kröger (York, UK - Wound Repair Regen.). This work aimed to provide a comprehensive summary of the current knowledge regarding the ultrastructure of the abdominal wall and how incisions affect its mechanical integrity.

A Comparative Study of Topical Treatments for the Management of Chronic Leg Ulcers in a Multi-Center Cohort - Cureus.com
Article by Ayman Fakhry, Sohiel Nagib, Abdullah H. Al-Mallah, Eslam M. Barsim et al. (Egypt, Roumania, UK). The choice of topical dressing significantly influences healing outcomes in patients with chronic leg ulcers. A combined enzymatic, antimicrobial, and moisture-retentive formulation was associated with faster healing and higher rates of complete ulcer closure compared with antimicrobial or hyaluronic acid therapy alone. The authors' findings support a more individualized, evidence-based approach to topical wound care as part of comprehensive chronic leg ulcer management.

A Skin Team Approach to Decrease Pressure Injuries in a Cardiothoracic Intensive Care Unit: A Quality Improvement Initiative - PubMed
Abstract by Aysa Arenas, Stephanie Sheldrick, Sarah Sutton, Jacqueline Gonzales et al. (Los Angeles, USA - J Wound Ostomy Continence Nurs.)

Cold microwave plasma jets for wound healing: antimicrobial efficacy, mechanisms and changes in microbial cells - Nature.com
Article by Kristína Trebulová, Veronika Loupová, Barbora Chobotská, Lukáš Kletzander et al. (Czech Republic, Poland - Scientific Reports). The analyses revealed progressive morphological and intracellular changes in yeast cells following the plasma treatment, including localized thinning and perforation of the cell wall, vacuole enlargement, enhanced vesicle formation, protoplast aggregation and leakage of intracellular content.

Why Diabetic Wounds Refuse To Heal: Scientists Uncover the Immune System’s Hidden Role - Scitechdaily.com
The authors highlight the potential for personalized treatment strategies based on immune profiling of individual wounds. Combination therapies that target multiple immune cell populations at the same time may also prove effective.

Case Report: Destructive deep infection of the foot caused by Neoscytalidium dimidiatum leading to great toe amputation - Frontiersin.org
Article by Huiyu Wang, Yiyun Xu, Hong Li, Ying Chen et al. (China - Front. Immunol.). Although typically a phytopathogen restricted to superficial human infections, it caused rapid necrosis necessitating hallux amputation. This case highlights the need for clinical awareness regarding the pathogenic potential of N. dimidiatum in immunocompromised hosts.

Negative Pressure Wound Therapy and Ultrasound Monitoring for Fracture-Related Infection of the Proximal Femur: A Case Report - Dovepress.com
Article by Yuru Shang, Shiyi Guo, Shukun Song, Mengying Tong et al. (China). This case shows that NPWT combined with ultrasound monitoring can control early fracture-related infection and allow implant retention. This treatment method may be applicable to areas with scarce medical resources. But larger-scale validation is still needed before clinical adoption.

Team develops 3D-printed bandage to help heal chronic wounds - Medicalxpress.com
Article by Clara Turnage. A team of University of Mississippi researchers is developing a way to use 3D-printed medicated patches to help close persistent sores and ulcers. The researchers in the School of Pharmacy have created a customizable wound scaffold that delivers natural, biodegradable antibacterials over time to encourage healing.

Bioprinting Human Skin: Could Lab-Grown Tissue Transform Wound Care? - Dermatology-centre.co.uk
Bioprinted skin represents something genuinely forward-looking in wound care, but it isn’t about overnight transformation. It’s about steady progress refining how your body heals, how scars form, and how reconstruction might one day feel less invasive and more personalised. The science is advancing quickly, yet it’s being guided by careful research, clinical testing and responsible regulation.

Chitosan-Hyaluronic Acid Composite Hydrogel with Slow-Release Hydrogen Sulfide and Cerium Oxide for Multifunctional Synergy to Promote Healing of Infected Wounds - Sciencedirect.com
Article by Xiaoqiang Wang, Kai Zhu, Wanxin Liu, Guoying Deng et al. (Shanghai, China - Int. J. of Nanomedicine). The developed gel dressing (NaSH@CeO2/CS-HA) intelligently regulates H2S release, combining antioxidant, antibacterial, and wound-healing functions into one, providing a comprehensive treatment solution for chronic infectious wounds with significant clinical application potential.

Orchestrating diabetic wound healing via a bio-inspired and dual-modal scaffold: integrating photothermal nanozymes and exosome-mediated immunomodulation - Sciencedirect.com
Article by Dashuai Li, Zijian Lin, Wanyi Zhao, Liqun Li and Pan Zhang (Zheijang, China - Materials & Design). Histological and transcriptomic analyses revealed enhanced collagen deposition, vascularization, and regulation of key signaling pathways involved in tissue remodeling. Consequently, HA-RHC-AP@MSC-Exo offers a synergistic therapeutic strategy for effective diabetic chronic wounds treatment.

Too Much or Too Little? A Molecular Switch That Decides How Wounds Heal - Newswise.com
Rather than suppressing inflammation indiscriminately, future therapies could aim to fine-tune NLRP3 activity in a phase-specific manner — enhancing its function during early inflammation while limiting its effects during later repair. Such strategies may accelerate closure while reducing fibrosis and improving tissue regeneration.

Pain relief in chronic wounds in older people and its impact on healing and quality of life - PubMed
Abstract by Linda Nazarko (United Kingdom - Br J Community Nurs.).

Wound care basics. An overview for nurses - Lww.com
Article by Jill Cox (Englewood, USA - Nursing). The clinical nurse may be the first caregiver to assess changes in a patient's skin and initiate wound care. Managing wounds can be challenging due to the diversity in types of wounds as well as the many options for topical management. The purpose of this article is to provide the nurse with the basic principles to aid in wound assessment and guide in the selection of appropriate topical treatment options for a variety of commonly encountered wounds.

Advanced Biomaterials in Tissue Engineering Based on Antibacterial and Antibiofilm Nanocomposites for Multidrug-Resistant Wound Pathogens - Acs.org
Article by Aizhan B. Talipova, Volodymyr Buranych, Irina S. Savitskaya, Inara Abashidze et al. (Kazakhstan, Slovakia, Poland, Ukraine - ACS Omega). This work demonstrates a nonantibiotic strategy to combat biofilms through a synergistically designed biomaterial. Given its robust performance and multifunctionality, this platform is a promising candidate for the development of advanced therapeutic dressings in regenerative wound care.

Development of a Film-Forming Wound Dressing from Periplaneta americana Grease: Formulation, Characterization, and Bioevaluation - Mdpi.com
Article by Qian Wang, Zhuohui He, Siyu Ji, Jie Zhao et al. (Dali, China - Pharmaceuticals). Periplaneta americana grease was successfully formulated into a multifunctional film-forming agent that addresses key barriers to healing—infection, oxidative stress, and tissue regeneration. The results demonstrate its potential as an innovative therapeutic strategy for wound care.