Hungarian Wound Care Society

Scientists may have found why diabetic wounds refuse to heal - Sciencedaily.com
Chronic diabetic wounds may fail to heal because immune cells remain locked in damaging inflammatory states instead of transitioning toward tissue repair. Researchers are exploring treatments that reprogram these immune responses, raising hopes for more targeted and effective therapies for diabetic ulcers.

Are we spending 4% of healthcare budgets on chronic wounds, yet missing half the problem? - Medtecheurope.org
Article by Judith A. Hargreaves. The challenge is not just how to heal wounds faster, but how to better support the people living with them. If up to 4% of healthcare budgets is already being spent on chronic wound care, addressing psychological and emotional wellbeing alongside physical treatment may be one of the most meaningful opportunities to improve outcomes, enhance quality of life, and reduce long-term healthcare costs.

Diagnostic Accuracy of Pressure Injury Staging Among Nurses: A Multisite Study Using Knowledge Assessment and Image-Based Evaluation - PubMed
Abstract by Nahla AbdulGadir Tayyib and Mousa Yahya Asiri (Saudi Arabia - Int Wound J).

An Update on Post-Surgical Wound Healing Management and Lower-Cost Alternatives: A Narrative Review for Healthcare Providers - PubMed
Abstract by Joseph D Quick, Lauren E Powell, Aneesh Syal, Neej N Patel et al. (USA - Health Sci Rep).

Vanilla Ingredient Could Help Heal Wounds - The-scientist.com
Article by R. J. Mackenzie (Glasgow, UK). Vanillin is more likely to be found in the hospital cafeteria than in a treatment ward, but researchers are investigating whether the molecule, used for its characteristic flavor in ice cream and other tasty goods, might also help close wounds more quickly.

Smart Textiles Tackle Wound Healing, Climate Adaptation, and Reproductive Health - Jmir.org
Article by Virginia Gewin. Smart textiles are moving from sensing to programmable actions. Technical advances such as conductive yarns, flexible sensors, and advanced nanomaterials are shaping the next generation of smart textiles. Washability, durability, and cost are the biggest challenges.

Heel-Free Compression Bandaging for Venous Leg Ulcers: A Non-Inferiority Trial of Interface Pressure - PubMed
Abstract by Anne Mauvilain, Cécile Durant, Annastasia Voisine, Bastien Perrot and Emmanuelle Cartron (France - Int Wound J.).

Potential of Chitosan-Based Systems Integrating Therapeutic Ions, Mesoporous Silica and SPIONs as Next-Generation Multifunctional Platforms for Diabetic Wound Healing - Mdpi.com
Article by Radhika Radhika, Diana C. Lago and Zulema Vargas-Osorio (Slovakia, Spain - Marine Drugs). This review explores the development of smart chitosan-based wound dressings integrating therapeutic ions, mesoporous silica, and superparamagnetic iron oxide nanoparticles (SPIONs). By combating infection, stimulating angiogenesis, and enabling targeted drug delivery, this multifunctional platform provides a comprehensive approach to the treatment and diagnostics of chronic diabetic wounds.

Patient-reported outcomes in venous leg ulcers: results from a prospective multicenter single-arm cohort study of silicone superabsorbent polymer dressings - Tandfonline.com
Article by Sebastian Probst, Vladica Veličković, Jacek Mikosinski, Konrad Panczak et al. (Switzerland, Germany, Poland - Patient Related Outcome Measures). Silicone superabsorbent polymer dressings used with compression were associated with improved quality of life and high patient-perceived benefit. Findings support incorporating validated patient-reported outcomes in VLU research and warrant larger comparative studies.

Hair Follicle-Derived Grafting for Chronic Cutaneous Wounds: A Systematic Review of Clinical Outcomes - Wiley.com
Article by Mara Hartoyo, Mounika Vattigunta and Jose A. Jaller (Miami, USA - International Wound Journal). Comparative studies consistently demonstrated superior wound healing with hair follicle-containing grafts relative to inter-wound or between-patient controls. Adverse events were limited and mild. Hair follicle-based grafting may be a potential solution for chronic nonhealing wounds, particularly in recalcitrant wounds.

Modern Burn Surgery: Operative Decisions From Acute Excision to Long-Term Reconstruction - Cureus.com
Article by Daniel Gravino (Msida, Malta). Burn surgery has evolved from simple wound closure to biologically informed, function-preserving reconstruction across the entire burn care pathway. Although significant advances have been achieved, further high-quality comparative research is required to define optimal surgical strategies and facilitate the safe integration of emerging regenerative technologies into routine clinical practice.

Research Progress on Artificial Intelligence in the Management of Diabetic Foot Ulcers - Dovepress.com
Article by Jinxia Du, Xiaoli Liu, Guihui Wu, Yin Huang et al. (Chengdu, China - Diabetes, Metabolic Syndrome and Obesity). The emergence of artificial intelligence (AI) technology offers new approaches to addressing these challenges. Based on recent domestic and international literature, this paper systematically reviews the research progress of artificial intelligence in the care of diabetic foot ulcers, focusing on four key dimensions.

Next-generation smart polymeric hydrogels for chronic wound management: integrating antimicrobial, immunomodulatory and regenerative strategies - Rsc.org
Article by Muhammad Bilal Habib, Laiba Arshad, Muhammad Kamran, Ghanwa Batool et al. (Pakistan - RSC Advances). This study provides a comprehensive technical assessment of next-generation polymeric hydrogels as precision platforms for advanced wound management.

A new approach to treating chronic wounds: Patch brings light to wound care - Admin.ch
A wound sensor, such as the one developed by Empa in 2025, would enable further development of the patch: Silicon dioxide nanoparticles can be loaded not only with a wound disinfectant but also with other therapeutic agents, and the polymer coating can be equipped with different photoswitches. Depending on the wavelength of the light used to irradiate the patch, different photoswitches are activated. The wound could thus be treated specifically with exactly the active ingredient needed at any given moment based on the detected bacterial infection.

Applications of Nanomaterials in Chronic Wound Healing and Scar Prevention - Nih.gov
Article by Nanxin Zhang, Bendian Song and Rongtao Cui (Shandong, China - Int J Nanomedicine). This review provides a theoretical basis and research guidance for utilizing nanotechnology to overcome barriers to chronic wound healing and prevent pathological scarring.

Antimicrobial Strategies for Chronic Cutaneous Ulcers: From Preclinical Nanotechnology to Clinical Practice - Tandfonline.com
Article by Myriam González, Gabriela E Galarza-Arévalo, Cristina Garzón-Romero and Maria P Romero (Quito, Ecuador - Int J Nanomedicine). This review critically evaluates current clinical and preclinical advances in the treatment of chronic cutaneous ulcers, with a focus on novel therapeutic modalities and emerging nanotechnology-based approaches.

Current Incisional Negative Pressure Wound Therapy Systems: Technical Characteristics and a Decision Framework for Device Selection - Wiley.com
Article by Luca Folini, Alfio Luca Costa, Claudio Ligresti, Pasquale Zona et al. (Padova, Italy - International Wound Journal). Incisional negative pressure wound therapy (iNPWT) should be used selectively, as an adjunct to standard preventive measures rather than routinely. Trials evaluate complete proprietary systems, and current evidence does not establish a hierarchy among commercially available devices. Once iNPWT is indicated, device choice can be guided by fluid-handling need, skin tolerance, seal feasibility and therapy duration; the framework requires prospective validation.

This Honeybee Silk Film Could Transform How Chronic Wounds Are Treated - Scitechdaily.com
Researchers from CSIRO and Adelaide University have tested a biodegradable film made from engineered honeybee silk as a possible foundation for a new generation of wound dressings. CSIRO developed and produced the recombinant silk film, while the Adelaide University team supplied wound-healing expertise and conducted the laboratory tests.

Investigating the wound healing potential of low‑power 661 nm laser light in a pigmented hairless murine model - D-nb.info
Article by Dimitra Statha, Ioannis Sfiniadakis, Michail Rallis, Jane Anastassopoulou and Eleni Alexandratou (Athens, Greece - Photochemical & Photobiological Sciences). This study highlights the critical need for further investigation into the parameters of photobiomodulation to ensure its effective application to the different skin phototypes and to mitigate potential adverse effects arising from incorrect usage.

Negative Pressure Wound Therapy in Infected and Complicated Wounds in Obstetrics and Gynecology: A Retrospective Comparative Study - Dergipark.org.tr
Article by Abdullah Tok, Alev Özer, Serdar Özer, Şakir Aydoğdu et al. (Turkey - Cukurova). A significant difference was observed in wound closure strategy, as 100% of patients in the VAC group underwent delayed resuturing, whereas alternative closure or secondary healing approaches were used in the conventional dressing group. VAC therapy was predominantly applied in patients with more complex surgical indications and higher baseline risk profiles.

Healthcare Professionals' Experiences of the Causes of Recurrent Pressure Injuries — A Phenomenographic Study - Wiley.com
Article by Mari Nööjd, Moustafa Elmasry and Ingrid Steinvall (Linköping, Sweden - International Wound Journal). This study adds a focus on experienced causes specific to recurrent pressure injuries, an area that has previously been neglected both in research and in clinical practice. The causes are described as stemming from various structural levels within society, whilst preventive measures have primarily been assigned at the patient and healthcare staff levels, which has led to ineffective interventions.

Empathy as Therapeutic Infrastructure in Wound Care: A Conceptual Synthesis - Wiley.com
Article by Sebastian Probst and Peta Tehan (Switzerland, Australia, Ireland - International Wound Journal). Empathy in wound care operates across relational, clinical, and organisational dimensions rather than as an isolated interpersonal skill. Empathetic care supports trust, treatment engagement, adherence, and continuity of care for people living with chronic wounds. Conceptualising empathy as therapeutic infrastructure highlights the need to embed empathy within healthcare systems, education, and wound care practice.

Living bio interfaces for chronic wounds: Next generation scaffolds for the spatiotemporal delivery of Lactiplantibacillus plantarum - Sciencedirect.com
Article by Anshad O C, Anoop Narayanan, Vijayashree R, Vaibhavi Uday Gurav et al. (India - Next Materials). Living hydrogels and cryosponges help preserve bacterial viability in wound sites. Nanozyme prebiotic co-delivery uses L. plantarum's metabolic resilience to clear multidrug-resistant biofilms. A translational roadmap is proposed to navigate regulatory frameworks for Live Biotherapeutic Products (LBPs).

New consensus document highlights need to address post-operative blistering to improve patient outcomes - Molnlycke.com
A new international consensus document on post-operative blistering in surgical incision wounds reflects this commitment. Developed by a global panel of experts in partnership with the World Union of Wound Healing Societies (WUWHS), the publication brings together the latest evidence and expert perspectives on a complication that can affect patient comfort, wound healing, infection risk and recovery.

Incidence and Risk Factors of Pressure Injury in Adult ICU Patients: A Prospective Cohort Study - PubMed
Abstract by Rajini Peter, K N Ashwini, P Dhivya, Aljo Joy and Selmar Mellisha (Nagpur, India - Nurs Crit Care).

The effect of compression stockings on patients with lower extremity venous ulcers: A meta-analysis - PubMed
Abstract by Huan Wang, Jianmei Gong, Dongmei Han, Xiaoyuan Wang et al. (China - Phlebology).

A Prospective Cohort Study of Hard-to-Heal Chronic Foot and Leg Wounds Followed for up to 20 Weeks After Initiation of ReGenerating Tissue Agents (RGTA) Technology as an Add-on to Optimal Local Care - Wiley.com
Article by Serge Ynesta, Marion Mourgues, Chloé Geri, Martin Inizan et al. (France - Int. Wound J.). This open-label study confirms the performance and tolerability of RGTA in a population of patients with particularly hard-to-heal chronic ulcers.

Thermotherapy for Chronic Wounds: A Wound-Interface Translation Framework for Materials, Devices, Clinical Evidence, and Validation Requirements - Mdpi.com
Article by Sameer Ahmad Hasan, Bassam Al-Naami, Muhammad Al-Ayyad, Abdel-Razzak Al-Hinnawi and Olga Korostynska (Jordan, Norway - Bioenginereeing). Clinical translation depends on reproducible wound-interface dosing under realistic moisture, pressure, perfusion, dressing, motion, and workflow conditions, together with wound-specific dose models, transparent reporting, realistic interface validation, and architecture-specific regulatory evidence.

Successful Limb Salvage Using Staged Applications of a Fish-Skin Xenograft (Kerecis) in a Heel Pad Degloving Injury: A Case Report - Nih.gov
Article by Dylan Parry, Dylan J Stephens, Caroline J Cushman, Emily Uyen Thai et al. (USA - J Orthop Case Rep.). This case demonstrates the potential role of staged fish-skin xenograft application as a biologically active reconstructive adjunct for wound-bed preparation and limb salvage in complex heel pad degloving injuries. In situations where immediate flap reconstruction is undesirable, and limb salvage remains the patient’s goal, staged xenograft reconstruction may expand the reconstructive armamentarium while preserving ambulatory function.

The Effectiveness of Autologous Platelet-Rich Plasma Topical Application Versus Injection in the Healing of Chronic Venous Ulcers - Cureus.com
Article by Neeraja Neena Nair and Thrishuli PB (Mysuru, India). Autologous PRP is a safe and effective adjunct for chronic VLUs. Both PRP topical application and injection improved healing compared with saline dressing, while PRP injection achieved earlier healing, greater ulcer area reduction, and shorter healing time, making it the preferred PRP delivery method.

Dual-Component Nanoemulsion Containing Brugmansia suaveolens Leaf Extract and Copaiba Oil: Antimicrobial Activity and Preclinical Wound-Healing Potential - Mdpi.com
Article by Sandro Pinheiro da Costa, Verônica da Silva Cardoso, Alane Beatriz Vermelho, Marcel Vasconcellos et al. (Brazil, Portugal - Plants). The authors' findings support the preclinical wound-repair potential of BSLE-NE as a dual-component topical formulation integrating BSLE and bioactive copaiba oil.

Pulsed Electromagnetic Fields Modulate Inflammatory and Tenogenic Responses in Human Tenocytes: Insights from Acute and Prolonged Inflammation Models - Nih.gov
Article by Michela Maria Taiana, Paola De Luca, Giulio Grieco, Enrico Ragni et al. (Italy - Cells). The authors' findings suggest that the inflammatory stage of tenocytes may influence pulsed electromagnetic fields responsiveness in vitro, highlighting the importance of considering this variable in the design of future clinical studies evaluating PEMF therapy for tendinopathy.

The Wounds We Don’t Heal: Reframing Palliative Wound Care in Podiatric Medicine - Mdpi.com
Article by Arthur Charles Evensen (Emporia, USA - JAPMA). Palliative wound care is not the absence of treatment, but a deliberate and goal-concordant approach to reducing suffering and preserving dignity. In patients with nonhealable wounds, success is not always defined by closure, but by the ability to improve comfort, maintain function, and enhance quality of life.

Negative Pressure Wound Therapy in Plastic and Reconstructive Surgery: A Contemporary Narrative Review of Current Evidence and Clinical Applications - Cureus.com
Article by Daniel Gravino (Msida, Malta). NPWT provides mechanical wound stabilisation, controlled exudate removal, reduction of dead space, and graft immobilisation. Its clinical application varies substantially between reconstructive indications, with some applications having a more established role than others. Potential complications include pain, periwound skin injury, bleeding, infection, seal failure, and tissue injury, emphasising the importance of appropriate patient selection and clinical monitoring. NPWT should be considered a reconstructive adjunct with a defined clinical objective rather than a universal wound-healing treatment. Its use should be integrated with appropriate debridement, assessment of perfusion, infection control, protection of critical structures, and timely definitive reconstruction.

Hyaluronic Acid-Based Biomaterials for Soft Tissue Repair and Wound Healing: Clinical Evidence and Emerging Applications - Nih.gov
Article by Bogdan Mircea Măciuceanu Zărnescu, Diana Cristina Pîrvulescu (Bunea), Adelina-Gabriela Niculescu, Alexandru Scafa Udriște et al. (Bucharest, Romania - Gels). This narrative review covers the clinical evidence for the effectiveness of commercial products for acute and diabetic wounds, as well as burns and chronic wounds, and discusses where their use is indicated. In the end, the current limitations of the research and future applications and directions are discussed.

A Narrative Review of Local Therapies in Diabetic Foot Ulcers: Promises, Limitations and Unmet Needs - PubMed
Abstract by Dured Dardari (France - J Diabetes Res.).

Hyperbaric Oxygen Therapy in Non-Healing Wounds: A Critical Narrative Review of Mechanisms, Clinical Applications and Outcomes - Journalajrimps.com
Article by Ketan Vagholkar (Navi Mumbai, India - Asian J of Res. in Med. and Pharmaceutical Scie.). This critical narrative review examines why mechanistic plausibility and clinical performance have diverged, and defines the conditions under which the therapy can be defended. Peer-reviewed literature was identified through structured searching of biomedical databases and open scholarly indexes, supplemented by backward and forward citation tracking, publisher records and retraction notices, with bibliographic details and digital object identifiers verified individually.

Rapid Pain Reduction and Wound Closure Following Treatment With an Amorphous Silica-Based Fiber Wound Matrix in Partial-Thickness Thermal Burns: A Case Report - Cureus.com
Article by Adam M. Jorgensen és William L. Hickerson (Winston Salem, USA). Because partial-thickness burns may spontaneously re-epithelialize, and this represents a single uncontrolled case with prior and concomitant treatment, causality cannot be established. The observed temporal pain response and wound-healing trajectory support prospective controlled evaluation using standardized pain, analgesic-use, epithelialization, functional, and safety endpoints.

Engineered human plasma-derived cryogels as a multifunctional scaffold to promote diabetic wound healing - Nih.gov
Article by Yueming Zhao, Jiajun Hu, Kairui Duan, Tingting Li et al. (Wenzhou, China - Mater Today Bio.). By converging native bioactivity with engineered material properties, the PlasmaMA cryogel creates a pro-healing microenvironment that actively orchestrates tissue repair. This work establishes a versatile human plasma-derived platform as a promising multifunctional therapy for complex wound healing.

Phytotherapeutic Regulation of Matrix Metalloproteinases in Diabetic Foot Ulcer: Molecular Mechanisms and Wound Healing Perspectives - Wiley.com
Article by Vishnu Priyan Elaiyaraja, Eswara Rajagopal, Subhikssha Babu and Balaji Sadhasivam (Erode, India - Phytochemicals in Food and Medicine). This review critically appraises the molecular dysregulations involved in DFU and the influence of bioactive compounds on wound‐healing pathways.

Mechanism and Component Study of Scorpion Peptides Regulation of Macrophage Polarization in Diabetic Wounds - Wiley.com
Article by Si Shi, Yarong Ding, Shuangxi Yang, Furong Zhu et al. (Changsha, China - Biomedicines). Scorpion peptides and their active peptide fragments block the activation of the NF-κB pathway by interfering with P65 phosphorylation and nuclear translocation, effectively inducing M2 polarization of macrophages, reducing inflammation and apoptosis, and ultimately promoting the healing of diabetic wounds.

Hydrogels in the Management of Peripheral Venous Disease: Bridging Material Design and Clinical Evidence - Mdpi.com
Article by Cristian-Adrian Silosi, Isabela Silosi, Mihai-Andrei Ruscu and Alexandra-Daniela Rotaru-Zavaleanu (Craiova, Romania - Gels). Authors summarize the physicochemical properties that determine hydrogel performance specifically under compression and in a heavily exudating wound, map hydrogel mechanisms of action onto venous pathobiology, survey therapeutic applications across the venous spectrum, including topical formulations for superficial venous thrombosis, and appraise the preclinical and clinical evidence with attention to why translation has stalled. They conclude by proposing design criteria for venous-specific hydrogel systems and methodological priorities for the trials needed to test them.

Effectiveness of negative-pressure wound therapy in partial-thickness and full-thickness burns: a systematic review - Scielo.br
Article by Vanessa Cindy Oliveira Neres Lima de Souza, Ana Caroliny da Silva, Ruy de Souza Lino Junior and Thauana Garcia da Silveira (Goiânia, Brazil - Acta Cir Bras.). NPWT provides benefits in burn treatment, including reduction of wound area, bacterial count, and re-epithelialization time, along with effectiveness in graft integration and healing quality. Despite limitations, such as application difficulties and prolonged treatment in pediatric patients, NPWT stands out for decreasing dressing changes, improving care logistics and psychological well-being.

Artificial Intelligence in Pressure Injury Diagnosis: A Critical Appraisal for Clinical Practice - PubMed
Abstract by Yuting Wei, Xiaodan Liu, Juhong Pei, Hongyan Zhang and Lin Han (Lanzhou, China - Adv Wound Care (New Rochelle).

A recent review on smart dressings for chronic wound management: from diagnosis to therapy - Rsc.org
Article by Zijian Dai, Zixian Zhang, Zahan Rabita, Yingmin Yan et al. (China - RSC Advances). Conventional dressings offer limited functionality and lack real-time feedback, driving the need for smart dressing systems that integrate diagnosis with on-demand therapy. This review summarizes the recent advances in smart wound dressings for chronic wound management.

Advances in incontinence-associated dermatitis: implications of the 2026 international best practice document - Cambridgemedia.com.com
Article by Michelle Barakat-Johnson and Dimitri Beeckman (Wound Practice and Research). While digital approaches to IAD assessment show emerging promise, further validation, including for algorithmic bias and skin tone diversity, is required before routine integration into practice. The revised guide provides a more structured and consistent framework to support improved clinical care and patient outcomes internationally.

Factors influencing sustainability of incontinent associated dermatitis prevention initiatives in a hospital setting - Cambridgemedia.com.com
Article by Leena Jacob, Valerie Wilson, Samara Geering, Josephine SF Chow and Gregory Melbourne (Wound Practice and Research). This article discusses the findings and challenges and it offers recommendations for continued improvement in IAD management and prevention practices.

Preventable pitfalls in negative pressure wound therapy: clinical lessons from four cases - Cambridgemedia.com.com
Article by Rabia Koca and Çağla Çiçek (Wound Practice and Research). The cases highlight that successful negative pressure wound therapy depends not only on appropriate indication but also on meticulous application and consistent monitoring. Structured clinical oversight and adherence to standardised principles may reduce avoidable complications and improve patient safety.

Probiotics and Extracellular Vesicles as Redox Modulators in Wound Healing: From Microbial Therapeutics to Engineered Nanotherapeutic Strategies - Mdpi.com
Article by Aline Yen Ling Wang, Ana Elena Aviña, Jerry Tsing-Kai Lin, Yen-Yu Liu et al. (Taiwan - Antioxidants). The evidence for the application of probiotic-derived EVs to wound healing is predominantly preclinical, and there is a lack of direct clinical evidence to date. EVs secreted from probiotics might hold potential for chronic wound care and redox-oriented regenerative medicine as a therapeutic platform.

Chronic Radiation-Induced Wounds: Pathogenesis, Current Therapeutic Strategies, and Emerging Regenerative Approaches - Mdpi.com
Article by Luyao Yu, Shangfei Gao, Cuicui Han, Jing Zhang et al. (Shanghai, China - IJMS). This review critically summarizes recent advances in pathogenic mechanisms and mechanism-based therapeutic strategies, highlighting current translational challenges and future directions for microenvironment-oriented regenerative therapies.

Nursing Roles in Diabetic Foot Ulcer Prevention, Wound Management, and Digital Monitoring - Jove.com
Article by Dangqin Ding, Aya Hamoud Alhaskawi, Jiayan Shen, Minwei Yang et al. (China - JoVe Journal). This article summarizes nurse-led strategies for managing diabetic foot ulcers, including patient education, systematic monitoring, advanced wound care, infection prevention, and emerging digital health technologies such as telemedicine and wearable sensors to improve early detection, treatment outcomes, and long-term prevention.

New Facile Testing Protocols to Assess Conformability of Advanced Dressings for Wound Healing - Mdpi.com
Article by Daniele Ghezzi and Gabriela Graziani (Italy - IJMS). The authors demonstrate that conformability can largely vary between different dressings but is not affected by either dressing size or exudate volume, whereas lateral spreading and time of absorption can be significantly affected by both parameters. They demonstrate that the tests succeed in predicting adaptability to wounds of complex shape in tissue models; hence it is suitable for a simple and cost-effective measure of conformability.

Lower Extremity Salvage Through Dextranomer Debridement and Evolution Toward a Functional Pincer in a Diabetic Foot: Experience in Rural Surgery - Cureus.com
Article by Kassandra Fabiola Hernandez Garcia (Monterrey, Mexico). This case illustrates that dextranomer is a low-cost, high-utility adjunct to aggressive surgical debridement for complex, infected diabetic foot wounds in resource-limited rural settings, and that a functional pincer-type anatomical outcome can preserve independent ambulation while avoiding infracondylar amputation.

Effects of Vacuum Compression Therapy on Healing of Chronic Lower Limb Ulcers: A Randomised Controlled Study - Mdpi.com
Abstract by Lenka Krupová, Miroslav Koliba, Yvetta Vantuchová, Vladimír Jetmar et al. (Ostrava, Czech Republic - Int Wound J.).

Formulation And Evaluation Of A Herbal Wound Healing Cream Using Neem, Aloe Vera, Turmeric And Tulsi - Ijpsjournal.com
Article by Sadanad Patil, Ganesh V Bansode, Joshi D.A., Parshuram Garad et al. (Hasegaon, India - Int J of Pharmaceutical Sciences). Neem and Tulsi show promising antimicrobial, antioxidant and wound-repair effects, although much of the evidence remains preclinical. A combined cream may therefore provide a rational multi-target formulation concept; however, synergy should not be assumed without direct formulation-specific testing. For a scientifically defensible product, extract identity, standardization, compatibility, stability, microbial quality, skin tolerability and wound-healing performance must be evaluated before any clinical claim is made.

Herb‐Based Chiral Nanomaterials: Potential Application in Wound Healing and Nanomedicine - Nih.gov
Article by Meng Sun, Zhuowei Ren, Hanyue Liang, Jie Gao et al. (China - Chirality). This research provides valuable insights for the design of herb‐functionalized formulations and lays a foundation for the development of advanced chiral nanomaterials with broad applications in nanomedicine.

Adult stem cell therapy for skin wound healing: A translational perspective from bench to bedside - Sciencedirect.com
Article by Rui Lei, Guan Li, Na Li, Shengli Lin et al. (China - Regenesis Repair Rehabilitation). Rather than pursuing increasingly complex cellular manipulations alone, progress may depend on refining how cells are expanded, assembled, and positioned within supportive microenvironments that enable stable, functionally integrated tissue repair. Through incremental but mechanism-informed optimization, adult stem cell–based strategies hold potential to improve both structural and functional restoration of injured human skin.

Therapeutic Potential of Microbial Exopolysaccharides in Skin Wound Healing: A Systematic Review and Meta-Analysis of In Vivo Experimental Studies in Rat Models - Mdpi.com
Article by Ana Taynara Ferreira de Melo, Joece Ferreira de Melo, Ezequiel Marcelino da Silva, Marcos Gontijo da Silva et al. (Tocantins, Brazil - Future Pharmacology). The authors' findings support the potential for translating EPS-based therapies from rodent models to human wounds, although the substantial heterogeneity of the evidence and the absence of clinical data indicate that controlled clinical trials remain essential to validate their application in humans.

Hydrogen Water and Wound Healing: What Recent Research Suggests -Hydrogen.com
Most wound care advice focuses on what you put on a wound. Almost none of it asks what's circulating underneath it — the water, the oxygen, the chemistry moving through tissue that's trying to close. Molecular hydrogen research has quietly built a case in that exact territory. Not as a bandage replacement. Not as a cure. As a redox signal that researchers keep finding at the center of how a wound actually repairs itself — from a Japanese hospital ward treating pressure ulcers to a 2026 diabetic-wound study using a hydrogen-infused dressing.

Clinical utility and medical necessity of high-purity type I collagen in hard-to-heal wound management: a review of evidence - Magonlinelibrary.com
Article by Windy Cole (Independence, USA - Journal of Wound Care). The author's findings validate high-purity type I collagen's medical necessity and economic value, underscoring its status as an advanced wound therapy with emerging supportive evidence rather than an experimental or investigational intervention.

Mechanical, Redox, and Bioelectrical Coupling in Hydrogels for Cutaneous Regeneration: Network Design and Structure–Property Relationships - Mdpi.com
Article by Luisbel González, Antonio Pérez-Torres, Yenisleidys Fernández-Guerrero, Daylenis Pérez et al. (Chile, Ecuador - Gels). Current evidence indicates that mechanoelectrical coupling is the most mature, whereas mechanoredox and redox–electrical interactions remain less systematically quantified. Moving beyond descriptive multifunctionality toward controllable cross-domain transduction may enable hydrogels to function as adaptive soft interfaces capable of responding to the evolving physicochemical conditions of cutaneous regeneration.

Establishment and translational evaluation of animal models for skin wound healing: a systematic review - Nih.gov
Article by Ying Zhang, Kai Leng, Miao Dong, Jinxuan Wu et al. (Shenyang, China - Front Physiol.). No single animal model perfectly recapitulates human cutaneous repair. Based on the synthesis of 129 studies, authors propose a hierarchical translational framework: utilizing genetically tractable mice for mechanistic discovery, rats for longitudinal pharmacological screening, and rabbits or porcine models for the validation of scar quality and epithelial closure prior to clinical trials.

Multifunctional Intelligent Hydrogels Based on MnO2 Nanozymes and Ca2+ Signal Regulation for Diabetic Wound Repair - Mdpi.com
Article by Yanling Li, Yuhan Mao, Ji’e Zhang, Lele Li, Rongfeng Zhao et al. (Ningbo, China - Gels). In this study, a multi-functional dynamically responsive composite hydrogel with high-efficiency antioxidant, antibacterial, and pro-angiogenic capacities was fabricated. Using SDS-C18 micelles as hydrophobic units, a rigid–flexible dual-network framework was constructed with polyvinyl alcohol and methacrylated hyaluronic acid.

Made Easy: Zinc oxide and ichthammol, A new approach to managing category 1 and 2 pressure ulcers and moisture-associated skin damage - Wounds-uk.com
Article by Jonathan Brady and Janine Davies. Despite advances in wound care, improving outcomes for patients with moisture-associated skin damages and pressure ulcers remains a challenge in practice. Zinc oxide medicated dressings protect fragile skin, reduce inflammation and support compression therapy where needed. Viscopaste and Ichthopaste remain effective, clinically relevant options within holistic, patient-centred community and tissue viability care.

Umbilical Cord-Derived Therapies for Wound Healing: A Scoping Review of Clinical and Translational Evidence - PubMed
Abstract by Juling Sia, Sandy Chua, Akimichi Morita, Bernett Lee and Hazel H Oon (Singapore, Japan - Exp Dermatol.).

Progress in the application of conductive hydrogels in wound healing: a review - Nih.gov
Article by Yun Lv, Yuting Li, Yueshuai Pan, Qianqian Li et al. (China - Nanoscale Adv.). This study focused on polymers suitable for conductive hydrogels, their functional mechanisms, and research advances in treating different types of wounds. It examined the key barriers to practical translation of conductive hydrogels and proposed future directions for their development as innovative wound dressings.

Technical Considerations for Wound Closure: A Plastic Surgery Perspective Part I - Sciencedirect.com
Article by Cleo Rowntree and Khong Yik Chew (UK, Singapore - Techniques in Vascular and Interventional Radiology). Integrating microvascular principles and biomechanical awareness into routine IR wound closure may reduce complication rates, improve access site durability, and minimize the need for reintervention in high-risk cohorts.

Risk factors for pressure ulcer development among adults undergoing surgery: a systematic review - PubMed
Abstract by Sadie Badrie, Pinar Avsar, Sherly George, Shijimol Kurian et al. (Dublin, Ireland - J Wound Care).

Fostering an Interdisciplinary Woundcare E-learning in Neglected Tropical Diseases for the World Health Organization, a Step Toward Lessening Function Loss - Archives-pmr.org
Abstract by Hubert Vuagnat, Michele Murdoch, Jannine Ebenso, Cristina Galván-Casas et al. (Geneva, Switzerland - Archives of Physical Medicine and Rehabilitation).

Multifunctional Silk Fibroin–Curcuminoid Films Combining Regenerative and Antioxidant Properties with pH Sensing for Wound Dressing Applications - Mdpi.com
Article by Rebecca Pellegrino, Maria Rosa Iaquinta, Annalia Masi, Mauro Pollini and Federica Paladini (Lecce, Italy - Biomimetics). The developed films represent a promising biomimetic platform for advanced wound dressings, capable of combining support for tissue regeneration, antioxidant protection, and visual monitoring of wound status through the detection of pH changes.

Moist Wound Healing Linked to Less Pain After Skin Grafting - Emjreviews.com
Moist wound healing shortened burn donor site recovery and eased pain and psychological symptoms after skin grafting. A retrospective cohort study of 173 adults found that a moisture preserving strategy was associated with faster healing, lower pain scores, and better skin and scar outcomes than traditional dry care using infrared irradiation.

Transforming wound care: the role of AI in achieving clinical and financial outcomes - PubMed
Abstract by Jackie Stephen Haynes and James Burford (UK - Br J Community Nurs.).

Preventing Hospital-Acquired Pressure Injuries: A Comprehensive Review of Evidence-Based Quality Improvement Initiatives in the Hospital Setting - PubMed
Abstract by Tamara L Oliver, Olivia Manning and Anne Schoening (Omaha, USA - J Nurs Care Qual.).

Algal Bioactive Metabolites with Important Roles in Wound Healing - Mdpi.com
Article by Tünay Karan, Çağrı Çağlar Sinmez, Sevgi Durna Daştan, Murat Çakir et al. (Turkey, Austria - Pharmaceutics). Algae contain pigments, peptides, fatty acids, and polysaccharides that are crucial for wound healing. These compounds play vital roles at all stages of the healing process by accelerating cell proliferation, promoting collagen deposition, scavenging reactive oxygen species (ROS), and regulating key inflammatory cytokines. Furthermore, their unique physical and functional properties enable the development of novel bio-inspired wound dressings, hydrogels, and drug-delivery scaffolds.

Sulfated Polysaccharides in Wound Healing: From Bioactive Materials Design to Regenerative Therapeutics - Dovepress.com
Article by Guangyun Hu, Ling Li, Ronglan Ouyang, Xiaosheng Ke et al. (China - Int. J. of Nanomedicine). This review outlines the sources, structural features, and engineering strategies of SPs, highlights the transition from natural to engineered systems, and discusses recent progress and translational challenges in SP-based wound therapeutics.

Natural Polysaccharide-Based Biomaterials for Skin Wound Healing: Immunomodulatory Mechanisms and Macrophage M2 Polarization - Mdpi.com
Article by Zhe Huang, Yubo Di, Luyao Wen, Xing He et al. (Xinxiang, China - Gels). This review highlights the studied materials as promising preclinical platforms for chronic wound management, although their clinical translation requires further validation.

Zinc Oxide Nanoparticles for Skin Burn Wound Healing: A Comprehensive Review of Multifunctional Nanotherapeutic and Sensor-Integrated Platforms - Mdpi.com
Article by Jharana Bajracharya, George Oguntala, Chinenye Anetekhai and Blessing Odu (Birmingham, UK - Applied Nano). Clinical translation is affected by several factors such as dose-dependent cytotoxicity associated with excessive ROS generation or dissolution, limited standardisation of green-synthesis methodologies, batch-to-batch variability in nanoparticle physicochemical properties and limited clinical trial data. ZnO-based theranostic platforms hold practical clinical translation potentials provided reproducible GMP-scale synthesis, long-term biocompatibility validation and comprehensive regulatory classification is systematically addressed.

Nano-Engineered Dressings for Infected Diabetic Wounds: Synergy of Catalysis, Delivery, and Fluid Management - Dovepress.com
Article by Xiaoyan Zhang and Ziwen Zhang (Jiaxing, China - Int. J. of Nanomedicine). This review systematically summarizes three cutting-edge strategies for nano-based wound dressings in the management of diabetic wound infections, including nanozyme catalytic therapy, nano-microneedle synergistic delivery systems, and Janus-structured intelligent fluid management, aiming to elucidate the mechanisms of action, synergistic rationale, and clinical translational prospects of these strategies.

Sesamin Promotes Diabetic Wound Healing by Inhibiting Ferroptosis via the SIRT1/Keap1/Nrf2 Pathway - Wiley.com
Abstract by Xin Wen, Sheng-tuo Zhou, Gao-sheng Zhu, Tao Xu et al. (Wenzhou, China - FASEB Journal).