Hungarian Wound Care Society

Maceration in wound care: Towards a standardised assessment scale - Woundsinternational.com
Article by Karen Ousey. Despite being a recognised consequence of excessive wound exudate, maceration remains underrepresented in formal education and routine wound assessments.

Clinical challenges and solutions in wound care - Britishjournalofnursing.com
Wound care and tissue viability continue to evolve at a remarkable pace. Increasing patient complexity, workforce pressures, antimicrobial resistance, and growing expectations for evidence-based practice have created both challenges and opportunities for clinicians.

Efficacy of Nanofat in Wound Healing: A Double-Blinded Randomized Controlled Trial - Lww.com
Article by Apinut Wongkietkachorn and Nuttapone Wongkietkachorn (Bangkok, Thailand - Plastic and Reconstructive Surgery). Nanofat significantly improved wound outcomes in abdominoplasty patients without associated complications such as oil cysts or fat necrosis.

Mild Heat Stimulating and Microenvironment Reprogramming Hydrogel for Accelerating Diabetic Wound Healing - Mdpi.com
Article by Xueting Xiao, Yannan Liu, Dan Li, Lebin Wang et al. (Xi'an, China - Gels). The green synthesized, mild heat-stimulating hydrogel establishes a synergistic microenvironment reprogramming paradigm for chronic diabetic wound managements.

To heal stubborn wounds, scientists look to nanomaterials - Knowablemagazine.org
For most people, a minor cut or scrape is no big deal — the body heals itself quickly, and antibiotics can deal with any infections. But some wounds, such as severe burns and diabetic ulcers, are prone to bacterial infections that can become resistant to antibiotics. Diabetic wounds are very difficult to heal and people live with these wounds for pretty much the rest of their life.

The Course of Scar Formation and Predictors of Scar Quality in 490 Paediatric Burn Patients During the First Year Post-Burn - Wiley.com
Article by Frederique M. Kemme, Inge M. L. Brantjes, Esther Middelkoop, Paul P. M. van Zuijlen et al. (The Netherlands - Wound Repair and Regeneration). Paediatric burn scars generally improve within the first year post-burn, most notably after 6 months, although pruritus remains common. Early scar characteristics appear informative for predicting scar outcomes. The authors' findings highlight the complexity of (predicting) scar formation and support early risk stratification for more personalised follow-up.

Topical Statin Therapy in Wound Healing: A Systemic Review of Therapeutic Outcomes - Wiley.com
Abstract by Scott Stratman, Caroline Campbell and Helen He (USA - Wound Repair and Regeneration).

Patient-Reported Outcomes and Wound-Related Quality of Life in Adults with Diabetic Foot Ulcers Treated with Silicone Superabsorbent Polymer Dressings: Exploratory Results from a Prospective Multicenter Nonrandomized Cohort Study - Dovepress.com
Article by David G Armstrong, Jacek Mikosinski, Konrad Panczak, Adam Wegrzynowski et al. (Medical Devices: Evidence and Research). In this prospective DFU cohort, use of silicone SAP dressings within a structured care setting was associated with improvements in wound area reduction and wound-related quality of life over 6 weeks. These results highlight the feasibility of integrating patient-reported outcomes in DFU studies and provide a clinically relevant platform for future comparative and health-economic evaluations.

Recent advances in flexible bioelectronics and intelligent wearable devices for wound management - Sciencedirect.com
Article by Huijuan Fu, Feng Qin, Zhechang Chen, Jiabao Ju et al. (China - Cell Reports Physical Science). This review aims to provide comprehensive insights for researchers and clinicians engaged in the development and application of flexible electronics and intelligent wearable devices for wound care.

Assessing the Outcomes and Complications of Skin Allografts in Healing Diabetic Foot and Venous Leg Ulcers: A Systematic Review of Randomised Controlled Trials - Wiley.com
Article by Christopher Mathe, Sachin Reddi, William Nahm, Aryaman Trikala and Samuel Schwartz (USA - International Wound Journal). The authors' findings provide comparative insight to guide clinical selection of skin substitutes and highlight the need for large-scale head-to-head trials to establish relative efficacy.

Polyherbal Wound Healing Potential of Lagenaria siceraria and Raphanus sativus: Phytochemistry, Pharmacological Wound Healing and Angiogenic Profiling of Dermal Endothelial Cells Isolated From People With Type 2 Diabetes - Wiley.com
Article by James Shadiow, Corey E. Mazo, Pallavi Varshney, Jeongjin J. Kim et al. (USA - The FASEB Journal). The authors' data reveal a complex interplay between cell-autonomous alterations and extrinsic signals in diabetic endothelial dysfunction. Therapeutic strategies targeting both intrinsic cellular programs (e.g., eNOS, Notch signaling) and the circulating milieu may represent promising avenues for enhancing wound repair in patients with T2D.

Telomerase is induced during wound healing across species - Oup.com
Article by David F Chang, Elizabeth A Olmsted-Davis, Aldona J Spiegel, John P Cooke and Biana Godin (Houston, USA - Skin Health and Disease). The authors' data demonstrate for the first time that, in three different mammalian species, there is a prominent intrinsic expression of TERT, highlighting a potentially important role of this enzyme in dermal wound repair. It has been shown that TERT is essential for cell renewal in highly proliferative organs in mice (e.g. bone marrow, spleen and the male reproductive system) and is able to rejuvenate cells in a murine model of senescence, extending an animal’s lifespan.

Polyherbal Wound Healing Potential of Lagenaria siceraria and Raphanus sativus: Phytochemistry, Pharmacological Activities, and Topical Gel Drug Delivery Systems – A Comprehensive Review - Ijpsjournal.com
Article by Anjali Rajput, Deepesh Lall and Ritesh Jain (Bilaspur, India - Int J of Pharmaceutical Sciences). The available scientific evidence supports the potential of Lagenaria siceraria and Raphanus sativus as effective natural agents for wound healing.

Outcomes of Self-Administered Outpatient Parenteral Antibiotic Therapy in Patients with Osteomyelitis of the Foot - Sagepub.com
Article by Arthur Tarricone, Allen Gee, Nitish Thirugnanasambandam, Dane K. Wukich et al. (USA - Int J of Lower Extremity Wounds). S-OPAT subjects demonstrated an increased association with binary wound healing at 90 days, hospitalization, and require longer antibiotic duration.

Operative management of penoscrotal elephantiasis - PubMed
Abstract by Vahudin Zugor, Mustapha Addali, Benjamin Hager and David Kajaia (Germany - Aktuelle Urol.).

Programmable device closes wounds - Eurekalert.org
Skin is our protective barrier from the outside world, and it is highly susceptible to damage. To prevent infection, restore protective skin cells, and reduce scarring, it is essential to quickly and robustly close a wound. A new study, published by Wiley in Advanced Science, showed that a multi-axis stretchable wound zipper (MSWZ) is effective in closing complex wounds quickly, improving wound healing. The MSWZ uses programmable force that can be personalized via mobile application, enhancing patient comfort and compliance.

Debridement in Modern Wound Care: The Impact of Technique Selection and Timing - Woundsource.com
Article by Jennifer J. Spector. Chronic wounds and biofilm-related complications continue to rise globally, making strategies such as debridement vital to patient outcomes. Selecting the appropriate debridement method requires careful consideration of wound etiology, patient comorbidities, care setting, vascular status, and overall treatment goals. Expanding evidence, emerging technologies, and increasing regulatory scrutiny are reshaping how clinicians approach debridement across the continuum of care.

Healing beyond the wound: social determinants in chronic vascular care. Perspectives from clinical practice - PubMed
Abstract by Davide Costa and Raffaele Serra (Catanzaro, Italy - Front Sociol.).

Targeting Biofilms in Chronic Wounds: Emerging Strategies with Antimicrobial Nanocomposites - Mdpi.com
Article by Ingrid D. Guerrero-Rodriguez, Chau M. Nguyen, Kytai T. Nguyen and Luis Soto-Garcia (Arlington, USA - JFB). In this review, authors discuss the pathophysiology of chronic wounds, the role of biofilms, microenvironmental changes, current treatments and their limitations, and nanocomposite-based strategies to eradicate biofilms and resolve chronic wounds.

Early Physiological Markers of Wound Healing as Potential Prognostic Markers of Long-Term Patient Satisfaction After Upper Eyelid Blepharoplasty: A Comparative Analysis of Aloe Vera Versus Untreated Controls - Cureus.com
Article by Abdullah Hayo and Ali Khalil (Lattakia, Syria). Early physiological response to Aloe Vera therapy, particularly reduction in vascularity and pigmentation within the first postoperative week, is strongly associated with patient satisfaction at three months following upper eyelid blepharoplasty. These findings provide surgeons with evidence-based prognostic markers for counseling patients and suggest that early wound appearance may serve as a reliable indicator of final aesthetic outcomes when Aloe Vera is used as an adjunctive therapy.

Wound Healing Activity of Iron Oxide Nanoparticles; Comparative In Vivo Study on Staphylococcus aureus-Infected and Non-Infected Wounds - Mdpi.com
Article by Marwa Reda Bakkar, Alaa M. Ali, Gehad E. Elkhouly, Nermeen R. Raya et al. (Egypt, Latvia, UK - Antibiotics). IONPs-CTAB might be a good therapeutic alternative for the management of infected and non-infected wounds. However, future studies are still required to assess their long-term safety and the possibility of their extravasation to systemic circulation, with their potential accumulation in various organs after a long-term application.

Chitosan-Based Wound Dressings: Property Modulation, Fabrication Strategies, and Emerging Applications in Tissue Regeneration - Dovepress.com
Article by Mingjie Fan, Xinmu Zhang, Longfei Lin, Ruying Tang et al. (China - Int J of Nanomedicine). Proactive bioactivity includes biocompatible and biodegradable property, antimicrobial property, hemostatic property and antioxidation property. The preparation techniques for wound dressings involve physical changes from liquid to solid, including crosslinking method, phase inversion, freeze-drying, electrospinning and solvent casting.

Emerging biomaterials for next-generation wound healing: From infection control to tissue regeneration - Sciencedirect.com
Abstract by Unqa Mustafa, Aiman Kaleem, Syeda Zunaira Bukhari, Hamna Riaz et al. (Pakistan, China, USA - Applied Materials Today).

Reconstruction of a Complex Pretibial Wound Using Dermal Regeneration Template and Split-Thickness Skin Graft - Cureus.com
Article by Abhya Niegocki, Caleb W. Brown, Nicole M. Ceausu, Brian Q. Le and Jeremy M. Powers (Johnson City, USA). The staged strategy offers a lower-risk alternative to traditional flap-based protocols for patients with significant co-morbidities, including transplant immunosuppression and peripheral arterial disease.

Electrospun PLGA–Propolis Scaffolds Regulate Collagen Architecture in Burn Wounds - Mdpi.com
Article by Kinga Orlińska, Paweł Olczyk, Przemysław Motyl, Mateusz Stojko et al. (Poland - IJMS). The authors' observations suggest that propolis incorporation is associated with improved collagen organization and tissue architecture at the histological level. The enhanced collagen deposition and organization observed in wounds treated with propolis-containing nonwovens indicate improved extracellular matrix remodeling and structural tissue organization in burned skin.

Clinical severity-dependent virulence of Staphylococcus aureus from human diabetic foot ulcers drives impaired wound healing in a diabetic murine model - Frontiersin.org
Article by Keun Seok Seo, Lee M. Nicols, Cara Dale Palmer, K. Taylor Hellmann et al. (USA - Front. Cell. Infect. Microbiol.). The authors' findings demonstrate that highly virulent S. aureus strains associated with severe DFUs exhibit enhanced virulence traits that promote host colonization and immune responses skewing macrophage polarization toward a sustained pro-inflammatory M1 phenotype, thereby exacerbating tissue damage and impairing wound healing.

Biological Foundations and Technological Advancements in the Use of Stem Cells in Regenerative Medicine Applied to Tissue Repair - Intechopen.com
Article by Marianna Galvão, Dallyne Souza and Adriana Bozzi. When combined with biomaterials and complementary therapies, MSC-based approaches represent a promising alternative to improve tissue repair outcomes.

The Effects of Malnutrition and Refeeding on Perioperative Wound Complications in Surgical Patients With Eating Disorders: A Narrative Review - Nature.com
Article by Sheilan Pouri and Harvey N. Mayrovitz (Davie, USA). The incidence of pressure ulcer (PU) in high-risk surgical patients can be reduced with targeted oral nutritional supplementation. Patients with EDs requiring surgical intervention need specific perioperative care to ensure optimal health outcomes. Preoperative nutrition screenings are essential, and postoperative cautious refeeding plans should include strict electrolyte and fluid intake monitoring. Multidisciplinary coordination, as the standard of care, may help reduce complications such as SSI, PU, and RS and support patients' wound-healing efforts.

Updated standards aim to improve wound repair - Eurekalert.org
Negative pressure wound therapy (NPWT) has become a central tool in modern wound care, helping clinicians manage complex wounds, support graft survival, and reduce postoperative infection risk. Yet its success depends on more than simply applying suction. Treatment decisions must account for wound type, infection status, drainage needs, dressing material, pressure level, and patient-specific risks. A newly updated expert consensus brings these factors into a clearer clinical framework. By reviewing recent evidence and translating it into scenario-based recommendations, the guidance aims to make NPWT use more standardized, safer, and more effective across wound repair, reconstructive surgery, burn care, and surgical site infection prevention.

The effects of platelet rich plasma and zinc oxide nanoparticle on skin wound healing in dogs - Nature.com
Article by Mona N. Wafy, Elham A. Hassan, Samar Saeed, Marwa S. Khattab et al. (Egypt - Scientific Reports). PRP–Lanolin and ZnO NPs offered moderate benefits but were less effective than PRP–ZnO NPs or PRP. ZnO NPs and PRP work together to improve skin wound healing in dogs; PRP promotes regenerative signaling, while ZnO NPs reduce oxidative stress and microbial load.

Murine Model of Radiation Dermatitis with Experimental Wound and Effects of Genistein - Mdpi.com
Article by Ernest O. N. Phillips, Amal Alzahrani, W. Bradley Rittase, John E. Slaven et al. (USA - Int J of Molecular Sciences). Cutaneous Radiation Injuries (CRIs) and wounds within an area of radiation exposure (combined injury, CI) are a significant concern for nuclear accidents and radiation combat/terrorist events. The authors' findings suggest that genistein may be an effective prophylactic against CRIs and CI.

Systematic Review of Wound Complications After Direct Anterior Approach Total Hip Arthroplasty: Incidence, Risk Factors, and Management Strategies - Lww.com
Abstract by Tejas Subramanian, Alexander Oles, Sereen Halayqeh, Michael Mazzucco et al. (USA - JAAOS).

Biomaterial-based approaches for diabetic wound healing - Sciencedirect.com
Article by Aiden Abenee Miriam D. Paculanan, Angela Mae D. Santos, Xyrille Yannah LL. Siapno, Joseph Rey H. Sta Agueda and Angelo Earvin Sy Choi (Manila - Philippines - Results in Engineering). Diabetic wounds require an intricate healing process due to complex wound conditions. Synthetic dressings lack bioactivity needed for effective diabetic wound repair. Biomaterials mimic native ECM to support cell adhesion and tissue regeneration. Bioactive compounds help modulate inflammation in diabetic wounds. Combining biomaterials improves scaffold strength and wound healing support.

Traditional Chinese medicinal strategies for enhanced wound healing: Mechanistic insights and translational advancements - Sciencedirect.com
Article by Dhamodharan Priyadharshini and Govindaraj Sabarees (Chennai, India - Pharmacological Research - Modern Chinese Medicine). TCM-based nano-enabled and biomaterial-assisted strategies represent multifunctional, stage-responsive wound therapies that integrate traditional pharmacological principles with modern regenerative medicine. Despite compelling preclinical evidence, clinical validation remains limited.

Optimized Wound Healing Assay to Study Extracellular Vesicle-Driven Glioblastoma Cell Migration - Mdpi.com
Article by Concetta D’Antonio, Francesca Mantile, Gabriella Pocsfalvi and Giovanna L. Liguori (Naples, Italy - MPs). The authors outline a step-by-step description of the procedure, detailing all required materials and equipment and highlighting critical steps, checkpoints, and key parameters. This method provides a robust framework for reproducible wound healing assays to investigate EV effects on GB cell migration.

Navigating Serous Drainage: What It Means for Your Health - Yourhealthmagazine.net
Serous drainage is typically normal in wound healing. Observe changes in volume, color, or odor that may indicate infection. Maintain cleanliness and proper dressing changes. Consult medical professionals if changes or concerns arise. Other drainage types can help identify healing stages and issues.