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News from the field of wound care and wound healing - September, 2026


Incidence and Risk Factors of Pressure Injury in Adult ICU Patients: A Prospective Cohort Study - PubMed
Abstract by Rajini Peter, K N Ashwini, P Dhivya, Aljo Joy and Selmar Mellisha (Nagpur, India - Nurs Crit Care).


The effect of compression stockings on patients with lower extremity venous ulcers: A meta-analysis - PubMed
Abstract by Huan Wang, Jianmei Gong, Dongmei Han, Xiaoyuan Wang et al. (China - Phlebology).


A Prospective Cohort Study of Hard-to-Heal Chronic Foot and Leg Wounds Followed for up to 20 Weeks After Initiation of ReGenerating Tissue Agents (RGTA) Technology as an Add-on to Optimal Local Care - Wiley.com
Article by Serge Ynesta, Marion Mourgues, Chloé Geri, Martin Inizan et al. (France - Int. Wound J.). This open-label study confirms the performance and tolerability of RGTA in a population of patients with particularly hard-to-heal chronic ulcers.


Thermotherapy for Chronic Wounds: A Wound-Interface Translation Framework for Materials, Devices, Clinical Evidence, and Validation Requirements - Mdpi.com
Article by Sameer Ahmad Hasan, Bassam Al-Naami, Muhammad Al-Ayyad, Abdel-Razzak Al-Hinnawi and Olga Korostynska (Jordan, Norway - Bioenginereeing). Clinical translation depends on reproducible wound-interface dosing under realistic moisture, pressure, perfusion, dressing, motion, and workflow conditions, together with wound-specific dose models, transparent reporting, realistic interface validation, and architecture-specific regulatory evidence.


Successful Limb Salvage Using Staged Applications of a Fish-Skin Xenograft (Kerecis) in a Heel Pad Degloving Injury: A Case Report - Nih.gov
Article by Dylan Parry, Dylan J Stephens, Caroline J Cushman, Emily Uyen Thai et al. (USA - J Orthop Case Rep.). This case demonstrates the potential role of staged fish-skin xenograft application as a biologically active reconstructive adjunct for wound-bed preparation and limb salvage in complex heel pad degloving injuries. In situations where immediate flap reconstruction is undesirable, and limb salvage remains the patient’s goal, staged xenograft reconstruction may expand the reconstructive armamentarium while preserving ambulatory function.


The Effectiveness of Autologous Platelet-Rich Plasma Topical Application Versus Injection in the Healing of Chronic Venous Ulcers - Cureus.com
Article by Neeraja Neena Nair and Thrishuli PB (Mysuru, India). Autologous PRP is a safe and effective adjunct for chronic VLUs. Both PRP topical application and injection improved healing compared with saline dressing, while PRP injection achieved earlier healing, greater ulcer area reduction, and shorter healing time, making it the preferred PRP delivery method.


Dual-Component Nanoemulsion Containing Brugmansia suaveolens Leaf Extract and Copaiba Oil: Antimicrobial Activity and Preclinical Wound-Healing Potential - Mdpi.com
Article by Sandro Pinheiro da Costa, Verônica da Silva Cardoso, Alane Beatriz Vermelho, Marcel Vasconcellos et al. (Brazil, Portugal - Plants). The authors' findings support the preclinical wound-repair potential of BSLE-NE as a dual-component topical formulation integrating BSLE and bioactive copaiba oil.


Pulsed Electromagnetic Fields Modulate Inflammatory and Tenogenic Responses in Human Tenocytes: Insights from Acute and Prolonged Inflammation Models - Nih.gov
Article by Michela Maria Taiana, Paola De Luca, Giulio Grieco, Enrico Ragni et al. (Italy - Cells). The authors' findings suggest that the inflammatory stage of tenocytes may influence pulsed electromagnetic fields responsiveness in vitro, highlighting the importance of considering this variable in the design of future clinical studies evaluating PEMF therapy for tendinopathy.


The Wounds We Don’t Heal: Reframing Palliative Wound Care in Podiatric Medicine - Mdpi.com
Article by Arthur Charles Evensen (Emporia, USA - JAPMA). Palliative wound care is not the absence of treatment, but a deliberate and goal-concordant approach to reducing suffering and preserving dignity. In patients with nonhealable wounds, success is not always defined by closure, but by the ability to improve comfort, maintain function, and enhance quality of life.


Negative Pressure Wound Therapy in Plastic and Reconstructive Surgery: A Contemporary Narrative Review of Current Evidence and Clinical Applications - Cureus.com
Article by Daniel Gravino (Msida, Malta). NPWT provides mechanical wound stabilisation, controlled exudate removal, reduction of dead space, and graft immobilisation. Its clinical application varies substantially between reconstructive indications, with some applications having a more established role than others. Potential complications include pain, periwound skin injury, bleeding, infection, seal failure, and tissue injury, emphasising the importance of appropriate patient selection and clinical monitoring. NPWT should be considered a reconstructive adjunct with a defined clinical objective rather than a universal wound-healing treatment. Its use should be integrated with appropriate debridement, assessment of perfusion, infection control, protection of critical structures, and timely definitive reconstruction.


Hyaluronic Acid-Based Biomaterials for Soft Tissue Repair and Wound Healing: Clinical Evidence and Emerging Applications - Nih.gov
Article by Bogdan Mircea Măciuceanu Zărnescu, Diana Cristina Pîrvulescu (Bunea), Adelina-Gabriela Niculescu, Alexandru Scafa Udriște et al. (Bucharest, Romania - Gels). This narrative review covers the clinical evidence for the effectiveness of commercial products for acute and diabetic wounds, as well as burns and chronic wounds, and discusses where their use is indicated. In the end, the current limitations of the research and future applications and directions are discussed.


A Narrative Review of Local Therapies in Diabetic Foot Ulcers: Promises, Limitations and Unmet Needs - PubMed
Abstract by Dured Dardari (France - J Diabetes Res.).


Hyperbaric Oxygen Therapy in Non-Healing Wounds: A Critical Narrative Review of Mechanisms, Clinical Applications and Outcomes - Journalajrimps.com
Article by Ketan Vagholkar (Navi Mumbai, India - Asian J of Res. in Med. and Pharmaceutical Scie.). This critical narrative review examines why mechanistic plausibility and clinical performance have diverged, and defines the conditions under which the therapy can be defended. Peer-reviewed literature was identified through structured searching of biomedical databases and open scholarly indexes, supplemented by backward and forward citation tracking, publisher records and retraction notices, with bibliographic details and digital object identifiers verified individually.


Rapid Pain Reduction and Wound Closure Following Treatment With an Amorphous Silica-Based Fiber Wound Matrix in Partial-Thickness Thermal Burns: A Case Report - Cureus.com
Article by Adam M. Jorgensen és William L. Hickerson (Winston Salem, USA). Because partial-thickness burns may spontaneously re-epithelialize, and this represents a single uncontrolled case with prior and concomitant treatment, causality cannot be established. The observed temporal pain response and wound-healing trajectory support prospective controlled evaluation using standardized pain, analgesic-use, epithelialization, functional, and safety endpoints.


Engineered human plasma-derived cryogels as a multifunctional scaffold to promote diabetic wound healing - Nih.gov
Article by Yueming Zhao, Jiajun Hu, Kairui Duan, Tingting Li et al. (Wenzhou, China - Mater Today Bio.). By converging native bioactivity with engineered material properties, the PlasmaMA cryogel creates a pro-healing microenvironment that actively orchestrates tissue repair. This work establishes a versatile human plasma-derived platform as a promising multifunctional therapy for complex wound healing.


Phytotherapeutic Regulation of Matrix Metalloproteinases in Diabetic Foot Ulcer: Molecular Mechanisms and Wound Healing Perspectives - Wiley.com
Article by Vishnu Priyan Elaiyaraja, Eswara Rajagopal, Subhikssha Babu and Balaji Sadhasivam (Erode, India - Phytochemicals in Food and Medicine). This review critically appraises the molecular dysregulations involved in DFU and the influence of bioactive compounds on wound‐healing pathways.


Mechanism and Component Study of Scorpion Peptides Regulation of Macrophage Polarization in Diabetic Wounds - Wiley.com
Article by Si Shi, Yarong Ding, Shuangxi Yang, Furong Zhu et al. (Changsha, China - Biomedicines). Scorpion peptides and their active peptide fragments block the activation of the NF-κB pathway by interfering with P65 phosphorylation and nuclear translocation, effectively inducing M2 polarization of macrophages, reducing inflammation and apoptosis, and ultimately promoting the healing of diabetic wounds.


Hydrogels in the Management of Peripheral Venous Disease: Bridging Material Design and Clinical Evidence - Mdpi.com
Article by Cristian-Adrian Silosi, Isabela Silosi, Mihai-Andrei Ruscu and Alexandra-Daniela Rotaru-Zavaleanu (Craiova, Romania - Gels). Authors summarize the physicochemical properties that determine hydrogel performance specifically under compression and in a heavily exudating wound, map hydrogel mechanisms of action onto venous pathobiology, survey therapeutic applications across the venous spectrum, including topical formulations for superficial venous thrombosis, and appraise the preclinical and clinical evidence with attention to why translation has stalled. They conclude by proposing design criteria for venous-specific hydrogel systems and methodological priorities for the trials needed to test them.


Effectiveness of negative-pressure wound therapy in partial-thickness and full-thickness burns: a systematic review - Scielo.br
Article by Vanessa Cindy Oliveira Neres Lima de Souza, Ana Caroliny da Silva, Ruy de Souza Lino Junior and Thauana Garcia da Silveira (Goiânia, Brazil - Acta Cir Bras.). NPWT provides benefits in burn treatment, including reduction of wound area, bacterial count, and re-epithelialization time, along with effectiveness in graft integration and healing quality. Despite limitations, such as application difficulties and prolonged treatment in pediatric patients, NPWT stands out for decreasing dressing changes, improving care logistics and psychological well-being.


Artificial Intelligence in Pressure Injury Diagnosis: A Critical Appraisal for Clinical Practice - PubMed
Abstract by Yuting Wei, Xiaodan Liu, Juhong Pei, Hongyan Zhang and Lin Han (Lanzhou, China - Adv Wound Care (New Rochelle).


A recent review on smart dressings for chronic wound management: from diagnosis to therapy - Rsc.org
Article by Zijian Dai, Zixian Zhang, Zahan Rabita, Yingmin Yan et al. (China - RSC Advances). Conventional dressings offer limited functionality and lack real-time feedback, driving the need for smart dressing systems that integrate diagnosis with on-demand therapy. This review summarizes the recent advances in smart wound dressings for chronic wound management.


Advances in incontinence-associated dermatitis: implications of the 2026 international best practice document - Cambridgemedia.com.com
Article by Michelle Barakat-Johnson and Dimitri Beeckman (Wound Practice and Research). While digital approaches to IAD assessment show emerging promise, further validation, including for algorithmic bias and skin tone diversity, is required before routine integration into practice. The revised guide provides a more structured and consistent framework to support improved clinical care and patient outcomes internationally.


Factors influencing sustainability of incontinent associated dermatitis prevention initiatives in a hospital setting - Cambridgemedia.com.com
Article by Leena Jacob, Valerie Wilson, Samara Geering, Josephine SF Chow and Gregory Melbourne (Wound Practice and Research). This article discusses the findings and challenges and it offers recommendations for continued improvement in IAD management and prevention practices.


Preventable pitfalls in negative pressure wound therapy: clinical lessons from four cases - Cambridgemedia.com.com
Article by Rabia Koca and Çağla Çiçek (Wound Practice and Research). The cases highlight that successful negative pressure wound therapy depends not only on appropriate indication but also on meticulous application and consistent monitoring. Structured clinical oversight and adherence to standardised principles may reduce avoidable complications and improve patient safety.


Probiotics and Extracellular Vesicles as Redox Modulators in Wound Healing: From Microbial Therapeutics to Engineered Nanotherapeutic Strategies - Mdpi.com
Article by Aline Yen Ling Wang, Ana Elena Aviña, Jerry Tsing-Kai Lin, Yen-Yu Liu et al. (Taiwan - Antioxidants). The evidence for the application of probiotic-derived EVs to wound healing is predominantly preclinical, and there is a lack of direct clinical evidence to date. EVs secreted from probiotics might hold potential for chronic wound care and redox-oriented regenerative medicine as a therapeutic platform.


Chronic Radiation-Induced Wounds: Pathogenesis, Current Therapeutic Strategies, and Emerging Regenerative Approaches - Mdpi.com
Article by Luyao Yu, Shangfei Gao, Cuicui Han, Jing Zhang et al. (Shanghai, China - IJMS). This review critically summarizes recent advances in pathogenic mechanisms and mechanism-based therapeutic strategies, highlighting current translational challenges and future directions for microenvironment-oriented regenerative therapies.


Nursing Roles in Diabetic Foot Ulcer Prevention, Wound Management, and Digital Monitoring - Jove.com
Article by Dangqin Ding, Aya Hamoud Alhaskawi, Jiayan Shen, Minwei Yang et al. (China - JoVe Journal). This article summarizes nurse-led strategies for managing diabetic foot ulcers, including patient education, systematic monitoring, advanced wound care, infection prevention, and emerging digital health technologies such as telemedicine and wearable sensors to improve early detection, treatment outcomes, and long-term prevention.


New Facile Testing Protocols to Assess Conformability of Advanced Dressings for Wound Healing - Mdpi.com
Article by Daniele Ghezzi and Gabriela Graziani (Italy - IJMS). The authors demonstrate that conformability can largely vary between different dressings but is not affected by either dressing size or exudate volume, whereas lateral spreading and time of absorption can be significantly affected by both parameters. They demonstrate that the tests succeed in predicting adaptability to wounds of complex shape in tissue models; hence it is suitable for a simple and cost-effective measure of conformability.


Lower Extremity Salvage Through Dextranomer Debridement and Evolution Toward a Functional Pincer in a Diabetic Foot: Experience in Rural Surgery - Cureus.com
Article by Kassandra Fabiola Hernandez Garcia (Monterrey, Mexico). This case illustrates that dextranomer is a low-cost, high-utility adjunct to aggressive surgical debridement for complex, infected diabetic foot wounds in resource-limited rural settings, and that a functional pincer-type anatomical outcome can preserve independent ambulation while avoiding infracondylar amputation.


Effects of Vacuum Compression Therapy on Healing of Chronic Lower Limb Ulcers: A Randomised Controlled Study - Mdpi.com
Abstract by Lenka Krupová, Miroslav Koliba, Yvetta Vantuchová, Vladimír Jetmar et al. (Ostrava, Czech Republic - Int Wound J.).


Formulation And Evaluation Of A Herbal Wound Healing Cream Using Neem, Aloe Vera, Turmeric And Tulsi - Ijpsjournal.com
Article by Sadanad Patil, Ganesh V Bansode, Joshi D.A., Parshuram Garad et al. (Hasegaon, India - Int J of Pharmaceutical Sciences). Neem and Tulsi show promising antimicrobial, antioxidant and wound-repair effects, although much of the evidence remains preclinical. A combined cream may therefore provide a rational multi-target formulation concept; however, synergy should not be assumed without direct formulation-specific testing. For a scientifically defensible product, extract identity, standardization, compatibility, stability, microbial quality, skin tolerability and wound-healing performance must be evaluated before any clinical claim is made.


Herb‐Based Chiral Nanomaterials: Potential Application in Wound Healing and Nanomedicine - Nih.gov
Article by Meng Sun, Zhuowei Ren, Hanyue Liang, Jie Gao et al. (China - Chirality). This research provides valuable insights for the design of herb‐functionalized formulations and lays a foundation for the development of advanced chiral nanomaterials with broad applications in nanomedicine.


Adult stem cell therapy for skin wound healing: A translational perspective from bench to bedside - Sciencedirect.com
Article by Rui Lei, Guan Li, Na Li, Shengli Lin et al. (China - Regenesis Repair Rehabilitation). Rather than pursuing increasingly complex cellular manipulations alone, progress may depend on refining how cells are expanded, assembled, and positioned within supportive microenvironments that enable stable, functionally integrated tissue repair. Through incremental but mechanism-informed optimization, adult stem cell–based strategies hold potential to improve both structural and functional restoration of injured human skin.


Therapeutic Potential of Microbial Exopolysaccharides in Skin Wound Healing: A Systematic Review and Meta-Analysis of In Vivo Experimental Studies in Rat Models - Mdpi.com
Article by Ana Taynara Ferreira de Melo, Joece Ferreira de Melo, Ezequiel Marcelino da Silva, Marcos Gontijo da Silva et al. (Tocantins, Brazil - Future Pharmacology). The authors' findings support the potential for translating EPS-based therapies from rodent models to human wounds, although the substantial heterogeneity of the evidence and the absence of clinical data indicate that controlled clinical trials remain essential to validate their application in humans.


Hydrogen Water and Wound Healing: What Recent Research Suggests -Hydrogen.com
Most wound care advice focuses on what you put on a wound. Almost none of it asks what's circulating underneath it — the water, the oxygen, the chemistry moving through tissue that's trying to close. Molecular hydrogen research has quietly built a case in that exact territory. Not as a bandage replacement. Not as a cure. As a redox signal that researchers keep finding at the center of how a wound actually repairs itself — from a Japanese hospital ward treating pressure ulcers to a 2026 diabetic-wound study using a hydrogen-infused dressing.


Clinical utility and medical necessity of high-purity type I collagen in hard-to-heal wound management: a review of evidence - Magonlinelibrary.com
Article by Windy Cole (Independence, USA - Journal of Wound Care). The author's findings validate high-purity type I collagen's medical necessity and economic value, underscoring its status as an advanced wound therapy with emerging supportive evidence rather than an experimental or investigational intervention.


Mechanical, Redox, and Bioelectrical Coupling in Hydrogels for Cutaneous Regeneration: Network Design and Structure–Property Relationships - Mdpi.com
Article by Luisbel González, Antonio Pérez-Torres, Yenisleidys Fernández-Guerrero, Daylenis Pérez et al. (Chile, Ecuador - Gels). Current evidence indicates that mechanoelectrical coupling is the most mature, whereas mechanoredox and redox–electrical interactions remain less systematically quantified. Moving beyond descriptive multifunctionality toward controllable cross-domain transduction may enable hydrogels to function as adaptive soft interfaces capable of responding to the evolving physicochemical conditions of cutaneous regeneration.


Establishment and translational evaluation of animal models for skin wound healing: a systematic review - Nih.gov
Article by Ying Zhang, Kai Leng, Miao Dong, Jinxuan Wu et al. (Shenyang, China - Front Physiol.). No single animal model perfectly recapitulates human cutaneous repair. Based on the synthesis of 129 studies, authors propose a hierarchical translational framework: utilizing genetically tractable mice for mechanistic discovery, rats for longitudinal pharmacological screening, and rabbits or porcine models for the validation of scar quality and epithelial closure prior to clinical trials.


Multifunctional Intelligent Hydrogels Based on MnO2 Nanozymes and Ca2+ Signal Regulation for Diabetic Wound Repair - Mdpi.com
Article by Yanling Li, Yuhan Mao, Ji’e Zhang, Lele Li, Rongfeng Zhao et al. (Ningbo, China - Gels). In this study, a multi-functional dynamically responsive composite hydrogel with high-efficiency antioxidant, antibacterial, and pro-angiogenic capacities was fabricated. Using SDS-C18 micelles as hydrophobic units, a rigid–flexible dual-network framework was constructed with polyvinyl alcohol and methacrylated hyaluronic acid.


Made Easy: Zinc oxide and ichthammol, A new approach to managing category 1 and 2 pressure ulcers and moisture-associated skin damage - Wounds-uk.com
Article by Jonathan Brady and Janine Davies. Despite advances in wound care, improving outcomes for patients with moisture-associated skin damages and pressure ulcers remains a challenge in practice. Zinc oxide medicated dressings protect fragile skin, reduce inflammation and support compression therapy where needed. Viscopaste and Ichthopaste remain effective, clinically relevant options within holistic, patient-centred community and tissue viability care.


Umbilical Cord-Derived Therapies for Wound Healing: A Scoping Review of Clinical and Translational Evidence - PubMed
Abstract by Juling Sia, Sandy Chua, Akimichi Morita, Bernett Lee and Hazel H Oon (Singapore, Japan - Exp Dermatol.).


Progress in the application of conductive hydrogels in wound healing: a review - Nih.gov
Article by Yun Lv, Yuting Li, Yueshuai Pan, Qianqian Li et al. (China - Nanoscale Adv.). This study focused on polymers suitable for conductive hydrogels, their functional mechanisms, and research advances in treating different types of wounds. It examined the key barriers to practical translation of conductive hydrogels and proposed future directions for their development as innovative wound dressings.


Technical Considerations for Wound Closure: A Plastic Surgery Perspective Part I - Sciencedirect.com
Article by Cleo Rowntree and Khong Yik Chew (UK, Singapore - Techniques in Vascular and Interventional Radiology). Integrating microvascular principles and biomechanical awareness into routine IR wound closure may reduce complication rates, improve access site durability, and minimize the need for reintervention in high-risk cohorts.


Risk factors for pressure ulcer development among adults undergoing surgery: a systematic review - PubMed
Abstract by Sadie Badrie, Pinar Avsar, Sherly George, Shijimol Kurian et al. (Dublin, Ireland - J Wound Care).


Fostering an Interdisciplinary Woundcare E-learning in Neglected Tropical Diseases for the World Health Organization, a Step Toward Lessening Function Loss - Archives-pmr.org
Abstract by Hubert Vuagnat, Michele Murdoch, Jannine Ebenso, Cristina Galván-Casas et al. (Geneva, Switzerland - Archives of Physical Medicine and Rehabilitation).


Multifunctional Silk Fibroin–Curcuminoid Films Combining Regenerative and Antioxidant Properties with pH Sensing for Wound Dressing Applications - Mdpi.com
Article by Rebecca Pellegrino, Maria Rosa Iaquinta, Annalia Masi, Mauro Pollini and Federica Paladini (Lecce, Italy - Biomimetics). The developed films represent a promising biomimetic platform for advanced wound dressings, capable of combining support for tissue regeneration, antioxidant protection, and visual monitoring of wound status through the detection of pH changes.


Moist Wound Healing Linked to Less Pain After Skin Grafting - Emjreviews.com
Moist wound healing shortened burn donor site recovery and eased pain and psychological symptoms after skin grafting. A retrospective cohort study of 173 adults found that a moisture preserving strategy was associated with faster healing, lower pain scores, and better skin and scar outcomes than traditional dry care using infrared irradiation.


Transforming wound care: the role of AI in achieving clinical and financial outcomes - PubMed
Abstract by Jackie Stephen Haynes and James Burford (UK - Br J Community Nurs.).


Preventing Hospital-Acquired Pressure Injuries: A Comprehensive Review of Evidence-Based Quality Improvement Initiatives in the Hospital Setting - PubMed
Abstract by Tamara L Oliver, Olivia Manning and Anne Schoening (Omaha, USA - J Nurs Care Qual.).


Algal Bioactive Metabolites with Important Roles in Wound Healing - Mdpi.com
Article by Tünay Karan, Çağrı Çağlar Sinmez, Sevgi Durna Daştan, Murat Çakir et al. (Turkey, Austria - Pharmaceutics). Algae contain pigments, peptides, fatty acids, and polysaccharides that are crucial for wound healing. These compounds play vital roles at all stages of the healing process by accelerating cell proliferation, promoting collagen deposition, scavenging reactive oxygen species (ROS), and regulating key inflammatory cytokines. Furthermore, their unique physical and functional properties enable the development of novel bio-inspired wound dressings, hydrogels, and drug-delivery scaffolds.


Sulfated Polysaccharides in Wound Healing: From Bioactive Materials Design to Regenerative Therapeutics - Dovepress.com
Article by Guangyun Hu, Ling Li, Ronglan Ouyang, Xiaosheng Ke et al. (China - Int. J. of Nanomedicine). This review outlines the sources, structural features, and engineering strategies of SPs, highlights the transition from natural to engineered systems, and discusses recent progress and translational challenges in SP-based wound therapeutics.


Natural Polysaccharide-Based Biomaterials for Skin Wound Healing: Immunomodulatory Mechanisms and Macrophage M2 Polarization - Mdpi.com
Article by Zhe Huang, Yubo Di, Luyao Wen, Xing He et al. (Xinxiang, China - Gels). This review highlights the studied materials as promising preclinical platforms for chronic wound management, although their clinical translation requires further validation.


Zinc Oxide Nanoparticles for Skin Burn Wound Healing: A Comprehensive Review of Multifunctional Nanotherapeutic and Sensor-Integrated Platforms - Mdpi.com
Article by Jharana Bajracharya, George Oguntala, Chinenye Anetekhai and Blessing Odu (Birmingham, UK - Applied Nano). Clinical translation is affected by several factors such as dose-dependent cytotoxicity associated with excessive ROS generation or dissolution, limited standardisation of green-synthesis methodologies, batch-to-batch variability in nanoparticle physicochemical properties and limited clinical trial data. ZnO-based theranostic platforms hold practical clinical translation potentials provided reproducible GMP-scale synthesis, long-term biocompatibility validation and comprehensive regulatory classification is systematically addressed.


Nano-Engineered Dressings for Infected Diabetic Wounds: Synergy of Catalysis, Delivery, and Fluid Management - Dovepress.com
Article by Xiaoyan Zhang and Ziwen Zhang (Jiaxing, China - Int. J. of Nanomedicine). This review systematically summarizes three cutting-edge strategies for nano-based wound dressings in the management of diabetic wound infections, including nanozyme catalytic therapy, nano-microneedle synergistic delivery systems, and Janus-structured intelligent fluid management, aiming to elucidate the mechanisms of action, synergistic rationale, and clinical translational prospects of these strategies.


Sesamin Promotes Diabetic Wound Healing by Inhibiting Ferroptosis via the SIRT1/Keap1/Nrf2 Pathway - Wiley.com
Abstract by Xin Wen, Sheng-tuo Zhou, Gao-sheng Zhu, Tao Xu et al. (Wenzhou, China - FASEB Journal).